Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A5GFQ5

Entry ID Method Resolution Chain Position Source
AF-A5GFQ5-F1 Predicted AlphaFoldDB

4 variants for A5GFQ5

Variant ID(s) Position Change Description Diseaes Association Provenance
rs1111544317 11 P>A No EVA
rs80922904 40 P>L No EVA
rs713918736 82 D>G No EVA
rs706148547 257 I>L No EVA

No associated diseases with A5GFQ5

1 regional properties for A5GFQ5

Type Name Position InterPro Accession
domain Domain of unknown function DUF3456 56 - 212 IPR021852

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

1 GO annotations of molecular function

Name Definition
signaling receptor binding Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

1 GO annotations of biological process

Name Definition
innate immune response Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q0P5N1 CNPY3 Protein canopy homolog 3 Bos taurus (Bovine) PR
Q9BT09 CNPY3 Protein canopy homolog 3 Homo sapiens (Human) PR
Q8BQ47 Cnpy4 Protein canopy homolog 4 Mus musculus (Mouse) PR
A3KNS2 cnpy3 Protein canopy homolog 3 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MEPLPEPTSR PRLRPRPRCL LLLPLLLLLL LLLPAPELGP REARAEETDW VRLPSKCEVC
70 80 90 100 110 120
KYVAVELKSA FEETGKTKEV IDTGYGILDR KASGVKYTKS DLRLIEVTET ICKRLLDYSL
130 140 150 160 170 180
HKERTGSNRF AKGMSETFET LHNLVHKGVK VVMDIPYELW NETSAEVADL KKQCDVLVEE
190 200 210 220 230 240
FEEVIEDWYR NHQEEDLTQF LCANHVLKGK DTSCLAEQWS GKKGDTAALG GKKSKKKSSR
250 260 270 280
AKASGGGSKQ RKELGGIEGD PSPEEDEGIQ KASPLTHSPP DEL