Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8BP78

Entry ID Method Resolution Chain Position Source
AF-Q8BP78-F1 Predicted AlphaFoldDB

12 variants for Q8BP78

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389553078 6 G>D No EVA
rs3389536658 12 S>C No EVA
rs260894843 47 A>V No EVA
rs265124953 110 R>Q No EVA
rs3389532195 154 N>D No EVA
rs237118592 174 F>L No EVA
rs3409234635 175 C>S No EVA
rs249926894 237 T>M No EVA
rs233925295 246 K>R No EVA
rs215520167 252 P>S No EVA
rs247549847 256 A>V No EVA
rs3389445364 257 S>Y No EVA

No associated diseases with Q8BP78

No regional properties for Q8BP78

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8BP78

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.

1 GO annotations of biological process

Name Definition
dephosphorylation The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q70Z53 FRA10AC1 Protein FRA10AC1 Homo sapiens (Human) PR
Q5FVF1 Fra10ac1 Protein FRA10AC1 homolog Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MHGHGGYDSD FSDDEQGGGS SKKRKKTVED ELLLTKPFQK ERHGKVAHKQ VAADLLDREE
70 80 90 100 110 120
ARNRRFHLIA MDAYQRHTKF VNDYILYYGG KREDFKRLGE NDKTDLDVIR ENHRFLWNEE
130 140 150 160 170 180
DEADMTWEKR LAKKYYDKLF KEYCIADLSR YKENKFGFRW RIEKEVISGK GQFFCGNKCC
190 200 210 220 230 240
NEKEGLRSWE VNFGYTEHGE KRNALVKLRL CQECSFKLNF HHRRKEIKST KKKSKTTPEC
250 260 270 280 290 300
DESPRKKSRS PPSEEASKGK DEGHSSSKKS EDSRNRNAEE EDSASDSELW KGPLPETDEK
310
SQEEEFDDYF QDLFL