Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8BLA1

Entry ID Method Resolution Chain Position Source
AF-Q8BLA1-F1 Predicted AlphaFoldDB

No variants for Q8BLA1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8BLA1

No associated diseases with Q8BLA1

No regional properties for Q8BLA1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8BLA1

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cilium A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
alpha-tubulin binding Binding to the microtubule constituent protein alpha-tubulin.
beta-tubulin binding Binding to the microtubule constituent protein beta-tubulin.
tubulin binding Binding to monomeric or multimeric forms of tubulin, including microtubules.

4 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
defense response to tumor cell Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism.
negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of cell proliferation.
spermatogenesis The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9Y238 DLEC1 Deleted in lung and esophageal cancer protein 1 Homo sapiens (Human) PR
Q68FQ8 Dlec1 Deleted in lung and esophageal cancer protein 1 homolog Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MDSESKEEQQ CTASSAVMSS LETQFLSVPH QLESASLSWS IRKSLHSSTV LMDDCHFGFP
70 80 90 100 110 120
TRSLRAGFHA LPPLPEPQTL RLRPASLRTQ EISHLLARVF RNLYTAQVIG DDLSDSLIKA
130 140 150 160 170 180
RGSEDARHEE FLDQLQQARA IYKQRLDEAA MLERHIMQAR ARDIAETEHT TKQSRLQVVE
190 200 210 220 230 240
TPVKLPPVKT AFRWCLDSKL MRKHHLISTE DYYTDPVPFC PAPKDKSTLG CSKLTFSCEQ
250 260 270 280 290 300
RFLRKSELDR EAEEHCRQLT ECDDFEYTVD SLGSISKAKE RTTDSVKKTS RPKNKKWMEH
310 320 330 340 350 360
LQVPQRALDR RLLASMENRN HFLKNPRFFP PNTPHGGKSL IVPLSKPERR ASLNAEPEWS
370 380 390 400 410 420
CTDAPVFLAK PSVGFFTDYE IGPVYEMVIA LQNTTSTSRF LRVLPPSSPY FALGLGMFPG
430 440 450 460 470 480
KGGIVAPGMT CQYIVQFIPD CLGDFDDFIL VETQSPHTLV IPLQARRPPP VLTLSPVLDC
490 500 510 520 530 540
GHCLIGGVKI TKFICKNVGF SVGKFCIMPQ KSWPPPSFRA VATTGFVEQP PFGVMPSVFE
550 560 570 580 590 600
LAPGYAILLE VLFLPTGLGQ AEETFIIVCD NCQIKEVVVV GTGQLVALDL IHISGGKNEP
610 620 630
DPGELKDLTA QYFIRFEPEN VQSTPKKQLI IRNAT