Q68FQ8

PR
Gene name
Dlec1
Protein name
Deleted in lung and esophageal cancer protein 1 homolog
Names
Species
Rattus norvegicus (Rat)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-68 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q68FQ8

Entry ID Method Resolution Chain Position Source
AF-Q68FQ8-F1 Predicted AlphaFoldDB

No variants for Q68FQ8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q68FQ8

No associated diseases with Q68FQ8

No regional properties for Q68FQ8

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q68FQ8

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cilium A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
alpha-tubulin binding Binding to the microtubule constituent protein alpha-tubulin.
beta-tubulin binding Binding to the microtubule constituent protein beta-tubulin.
tubulin binding Binding to monomeric or multimeric forms of tubulin, including microtubules.

4 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
defense response to tumor cell Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism.
negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of cell proliferation.
spermatogenesis The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9Y238 DLEC1 Deleted in lung and esophageal cancer protein 1 Homo sapiens (Human) PR
Q8BLA1 Dlec1 Deleted in lung and esophageal cancer protein 1 homolog Mus musculus (Mouse) PR
10 20 30 40 50 60
MEPESKKELQ SPASSFVMSS ETMWESTPRQ PESTSLSWSP RKSLRSLTVF TDYCQFGYPT
70 80 90 100 110 120
RSLRAGFQEL PPLPEPQTLR LRPASLRTQD ISHLLARVFR NLYTAQVIGD DLSDSLIKAR
130 140 150 160 170 180
GSEDARHEEF LDQLQQARAI YKKRLDDVAM LEKHITQARA RDIAETEHAT KQGRLHVVEA
190 200 210 220 230 240
PVKLPPVKTV FRWCIDNELM QKHHLISTED YYNDPLPFCP APKRSPTPMY SKMTFSCEKR
250 260 270 280 290 300
FTHKSDLERK AEEHCRKLVE FDDLEYTTDS LRSVSKTKGK TKVTIKKAST PANKKWMEHL
310 320 330 340 350 360
QVPQRALDRR LLARMQNRNH YLKNPRFFPP NTPHGGKSLI VPSRKPERRG SLSAKPEWRC
370 380 390 400 410 420
VCSSRRIPGN VSFRVNLDLV YGGPQTLASQ GSVPEESGVL GSTSGMAFDP QGPRVRLFSA
430 440 450 460
VRSRGVDPWE PVWASSGHPK WGGAGAGAYS HVTLAWYVDY LFLLL