Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q84LH8

Entry ID Method Resolution Chain Position Source
AF-Q84LH8-F1 Predicted AlphaFoldDB

54 variants for Q84LH8

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06341356 9 N>K No 1000Genomes
tmp_3_21829865_C_A 11 E>* No 1000Genomes
tmp_3_21829843_G_A 18 T>I No 1000Genomes
tmp_3_21829840_T_C 19 N>S No 1000Genomes
ENSVATH06341355 23 I>F No 1000Genomes
ENSVATH14453754 25 P>R No 1000Genomes
ENSVATH12827841 46 R>H No 1000Genomes
ENSVATH06341350 49 P>S No 1000Genomes
tmp_3_21829575_A_C 67 I>S No 1000Genomes
ENSVATH06341349 70 D>E No 1000Genomes
ENSVATH02523723 76 Q>L No 1000Genomes
tmp_3_21829539_T_G 79 N>T No 1000Genomes
tmp_3_21829536_T_C 80 Y>C No 1000Genomes
ENSVATH00427028 83 L>P No 1000Genomes
tmp_3_21829489_G_A 96 P>S No 1000Genomes
tmp_3_21829450_A_T 109 S>T No 1000Genomes
ENSVATH06341348 115 I>V No 1000Genomes
ENSVATH12827838 142 K>N No 1000Genomes
ENSVATH06341345 147 V>A No 1000Genomes
ENSVATH06341342 155 C>S No 1000Genomes
ENSVATH12827837 162 N>K No 1000Genomes
ENSVATH06341341 175 D>Y No 1000Genomes
ENSVATH02523719 212 D>Y No 1000Genomes
ENSVATH02523718 223 Q>K No 1000Genomes
ENSVATH00427026 226 V>M No 1000Genomes
ENSVATH12827834 227 S>T No 1000Genomes
ENSVATH06341339 231 I>L No 1000Genomes
ENSVATH02523717 231 I>R No 1000Genomes
ENSVATH06341338 236 T>A No 1000Genomes
tmp_3_21829052_C_T 241 M>I No 1000Genomes
ENSVATH06341337 241 M>V No 1000Genomes
ENSVATH02523716 250 G>A No 1000Genomes
ENSVATH02523710 307 M>L No 1000Genomes
ENSVATH02523709 307 M>T No 1000Genomes
tmp_3_21828645_G_T 319 A>E No 1000Genomes
tmp_3_21828646_C_T 319 A>T No 1000Genomes
ENSVATH12827829 321 A>G No 1000Genomes
ENSVATH12827828 338 P>S No 1000Genomes
tmp_3_21828563_T_A 346 Q>H No 1000Genomes
ENSVATH02523707 354 F>L No 1000Genomes
ENSVATH12827827 355 P>S No 1000Genomes
ENSVATH06341326 369 V>A No 1000Genomes
ENSVATH00427022 373 P>T No 1000Genomes
ENSVATH06341325 380 A>E No 1000Genomes
tmp_3_21828457_T_G 382 N>H No 1000Genomes
tmp_3_21828454_G_T 383 Q>K No 1000Genomes
tmp_3_21828453_T_C 383 Q>R No 1000Genomes
ENSVATH06341324 393 M>I No 1000Genomes
ENSVATH02523705 394 G>A No 1000Genomes
tmp_3_21828417_C_A 395 G>V No 1000Genomes
ENSVATH06341318 407 Q>K No 1000Genomes
ENSVATH12827814 418 G>A No 1000Genomes
tmp_3_21828227_C_T 433 A>T No 1000Genomes
ENSVATH06341316 437 S>N No 1000Genomes

No associated diseases with Q84LH8

4 regional properties for Q84LH8

Type Name Position InterPro Accession
domain Helicase, C-terminal 394 - 553 IPR001650
domain Helicase/UvrB, N-terminal 166 - 332 IPR006935
domain Helicase superfamily 1/2, ATP-binding domain 162 - 361 IPR014001
domain Bacteriophage T5, Orf172 DNA-binding 5 - 77 IPR018306

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
promoter-specific chromatin binding Binding to a section of chromatin that is associated with gene promoter sequences of DNA.
protein dimerization activity The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

5 GO annotations of biological process

Name Definition
ethylene biosynthetic process The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
red, far-red light phototransduction The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.
regulation of auxin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
regulation of auxin mediated signaling pathway Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
response to low fluence blue light stimulus by blue low-fluence system Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8W2F3 PIF4 Transcription factor PIF4 Arabidopsis thaliana (Mouse-ear cress) PR
Q7XHI7 BHLH127 Transcription factor bHLH127 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEQVFADWNF EDNFHMSTNK RSIRPEDELV ELLWRDGQVV LQSQARREPS VQVQTHKQET
70 80 90 100 110 120
LRKPNNIFLD NQETVQKPNY AALDDQETVS WIQYPPDDVI DPFESEFSSH FFSSIDHLGG
130 140 150 160 170 180
PEKPRTIEET VKHEAQAMAP PKFRSSVITV GPSHCGSNQS TNIHQATTLP VSMSDRSKNV
190 200 210 220 230 240
EERLDTSSGG SSGCSYGRNN KETVSGTSVT IDRKRKHVMD ADQESVSQSD IGLTSTDDQT
250 260 270 280 290 300
MGNKSSQRSG STRRSRAAEV HNLSERRRRD RINERMKALQ ELIPHCSRTD KASILDEAID
310 320 330 340 350 360
YLKSLQMQLQ VMWMGSGMAA AAAAAASPMM FPGVQSSPYI NQMAMQSQMQ LSQFPVMNRS
370 380 390 400 410 420
APQNHPGLVC QNPVQLQLQA QNQILSEQLA RYMGGIPQMP PAGNQMQTVQ QQPADMLGFG
430 440
SPAGPQSQLS APATTDSLHM GKIG