Q84LH8
Gene name |
PIF5 (BHLH65, EN103, PIL6, At3g59060, F17J16.110) |
Protein name |
Transcription factor PIF5 |
Names |
Basic helix-loop-helix protein 65, AtbHLH65, bHLH 65, Phytochrome interacting factor-like 6, Phytochrome-interacting factor 5, Transcription factor EN 103, bHLH transcription factor bHLH065 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G59060 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q84LH8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q84LH8-F1 | Predicted | AlphaFoldDB |
54 variants for Q84LH8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH06341356 | 9 | N>K | No | 1000Genomes | |
| tmp_3_21829865_C_A | 11 | E>* | No | 1000Genomes | |
| tmp_3_21829843_G_A | 18 | T>I | No | 1000Genomes | |
| tmp_3_21829840_T_C | 19 | N>S | No | 1000Genomes | |
| ENSVATH06341355 | 23 | I>F | No | 1000Genomes | |
| ENSVATH14453754 | 25 | P>R | No | 1000Genomes | |
| ENSVATH12827841 | 46 | R>H | No | 1000Genomes | |
| ENSVATH06341350 | 49 | P>S | No | 1000Genomes | |
| tmp_3_21829575_A_C | 67 | I>S | No | 1000Genomes | |
| ENSVATH06341349 | 70 | D>E | No | 1000Genomes | |
| ENSVATH02523723 | 76 | Q>L | No | 1000Genomes | |
| tmp_3_21829539_T_G | 79 | N>T | No | 1000Genomes | |
| tmp_3_21829536_T_C | 80 | Y>C | No | 1000Genomes | |
| ENSVATH00427028 | 83 | L>P | No | 1000Genomes | |
| tmp_3_21829489_G_A | 96 | P>S | No | 1000Genomes | |
| tmp_3_21829450_A_T | 109 | S>T | No | 1000Genomes | |
| ENSVATH06341348 | 115 | I>V | No | 1000Genomes | |
| ENSVATH12827838 | 142 | K>N | No | 1000Genomes | |
| ENSVATH06341345 | 147 | V>A | No | 1000Genomes | |
| ENSVATH06341342 | 155 | C>S | No | 1000Genomes | |
| ENSVATH12827837 | 162 | N>K | No | 1000Genomes | |
| ENSVATH06341341 | 175 | D>Y | No | 1000Genomes | |
| ENSVATH02523719 | 212 | D>Y | No | 1000Genomes | |
| ENSVATH02523718 | 223 | Q>K | No | 1000Genomes | |
| ENSVATH00427026 | 226 | V>M | No | 1000Genomes | |
| ENSVATH12827834 | 227 | S>T | No | 1000Genomes | |
| ENSVATH06341339 | 231 | I>L | No | 1000Genomes | |
| ENSVATH02523717 | 231 | I>R | No | 1000Genomes | |
| ENSVATH06341338 | 236 | T>A | No | 1000Genomes | |
| tmp_3_21829052_C_T | 241 | M>I | No | 1000Genomes | |
| ENSVATH06341337 | 241 | M>V | No | 1000Genomes | |
| ENSVATH02523716 | 250 | G>A | No | 1000Genomes | |
| ENSVATH02523710 | 307 | M>L | No | 1000Genomes | |
| ENSVATH02523709 | 307 | M>T | No | 1000Genomes | |
| tmp_3_21828645_G_T | 319 | A>E | No | 1000Genomes | |
| tmp_3_21828646_C_T | 319 | A>T | No | 1000Genomes | |
| ENSVATH12827829 | 321 | A>G | No | 1000Genomes | |
| ENSVATH12827828 | 338 | P>S | No | 1000Genomes | |
| tmp_3_21828563_T_A | 346 | Q>H | No | 1000Genomes | |
| ENSVATH02523707 | 354 | F>L | No | 1000Genomes | |
| ENSVATH12827827 | 355 | P>S | No | 1000Genomes | |
| ENSVATH06341326 | 369 | V>A | No | 1000Genomes | |
| ENSVATH00427022 | 373 | P>T | No | 1000Genomes | |
| ENSVATH06341325 | 380 | A>E | No | 1000Genomes | |
| tmp_3_21828457_T_G | 382 | N>H | No | 1000Genomes | |
| tmp_3_21828454_G_T | 383 | Q>K | No | 1000Genomes | |
| tmp_3_21828453_T_C | 383 | Q>R | No | 1000Genomes | |
| ENSVATH06341324 | 393 | M>I | No | 1000Genomes | |
| ENSVATH02523705 | 394 | G>A | No | 1000Genomes | |
| tmp_3_21828417_C_A | 395 | G>V | No | 1000Genomes | |
| ENSVATH06341318 | 407 | Q>K | No | 1000Genomes | |
| ENSVATH12827814 | 418 | G>A | No | 1000Genomes | |
| tmp_3_21828227_C_T | 433 | A>T | No | 1000Genomes | |
| ENSVATH06341316 | 437 | S>N | No | 1000Genomes |
No associated diseases with Q84LH8
4 regional properties for Q84LH8
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| promoter-specific chromatin binding | Binding to a section of chromatin that is associated with gene promoter sequences of DNA. |
| protein dimerization activity | The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| ethylene biosynthetic process | The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. |
| red, far-red light phototransduction | The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm. |
| regulation of auxin biosynthetic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth. |
| regulation of auxin mediated signaling pathway | Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin. |
| response to low fluence blue light stimulus by blue low-fluence system | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEQVFADWNF | EDNFHMSTNK | RSIRPEDELV | ELLWRDGQVV | LQSQARREPS | VQVQTHKQET |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LRKPNNIFLD | NQETVQKPNY | AALDDQETVS | WIQYPPDDVI | DPFESEFSSH | FFSSIDHLGG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PEKPRTIEET | VKHEAQAMAP | PKFRSSVITV | GPSHCGSNQS | TNIHQATTLP | VSMSDRSKNV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EERLDTSSGG | SSGCSYGRNN | KETVSGTSVT | IDRKRKHVMD | ADQESVSQSD | IGLTSTDDQT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MGNKSSQRSG | STRRSRAAEV | HNLSERRRRD | RINERMKALQ | ELIPHCSRTD | KASILDEAID |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YLKSLQMQLQ | VMWMGSGMAA | AAAAAASPMM | FPGVQSSPYI | NQMAMQSQMQ | LSQFPVMNRS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| APQNHPGLVC | QNPVQLQLQA | QNQILSEQLA | RYMGGIPQMP | PAGNQMQTVQ | QQPADMLGFG |
| 430 | 440 | ||||
| SPAGPQSQLS | APATTDSLHM | GKIG |