Q80YR9

PR
Gene name
Rbm12b1 (Rbm12b, Rbm12ba)
Protein name
RNA-binding protein 12B-A
Names
RNA-binding motif protein 12B-A
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:72397
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

342-417 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q80YR9

Entry ID Method Resolution Chain Position Source
AF-Q80YR9-F1 Predicted AlphaFoldDB

31 variants for Q80YR9

Variant ID(s) Position Change Description Diseaes Association Provenance
rs864285639 99 G>R No EVA
rs3388676556 445 A>G No EVA
rs3388677224 449 F>L No EVA
rs27729842 486 V>I No EVA
rs3388674375 511 L>F No EVA
rs3388670348 514 L>V No EVA
rs1133694527 538 M>I No EVA
rs231574771 587 E>D No EVA
rs237835615 592 S>P No EVA
rs3388673386 601 H>R No EVA
rs258252041 605 R>H No EVA
rs3388676564 616 F>S No EVA
rs3388655177 630 E>V No EVA
rs220979792 634 Q>R No EVA
rs242916679 637 E>Q No EVA
rs578506864 652 A>T No EVA
rs3388676611 663 D>N No EVA
rs221213247 666 T>I No EVA
rs3388673403 671 L>S No EVA
rs230585525 702 R>T No EVA
rs240291270 704 P>S No EVA
rs229535445 721 G>V No EVA
rs246778384 726 L>Q No EVA
rs213309910 738 F>L No EVA
rs3388660062 741 F>L No EVA
rs227730979 742 P>L No EVA
rs227730979 742 P>R No EVA
rs3388670309 747 T>S No EVA
rs3388660121 763 K>M No EVA
rs3388670273 778 D>G No EVA
rs27729836 816 A>S No EVA

No associated diseases with Q80YR9

2 regional properties for Q80YR9

Type Name Position InterPro Accession
domain LEM domain 1 - 45 IPR003887
domain Emerin, LEM domain 4 - 46 IPR034989

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
regulation of RNA splicing Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8IXT5 RBM12B RNA-binding protein 12B Homo sapiens (Human) PR
Q66JV4 Rbm12b2 RNA-binding protein 12B-B Mus musculus (Mouse) PR
10 20 30 40 50 60
MAVVIRLLGL PFIAGPVDIR HFFKGLTIPD GGVHIIGGKV GEAFIIFATD EDARRAISRS
70 80 90 100 110 120
GGFIKDSSVE LFLSSKVEMQ KTIEMKRTAR VGRGRPGSGA SGVGNVYHFS DALKEEESYS
130 140 150 160 170 180
GYGSSVNRDA GFHTNGTGLD LRPRKTRPLK AENPYLFLRG LPYLVNEDDV RVFFSGLCVD
190 200 210 220 230 240
GVILLKHHDG RNNGDAIVKF ASCVDASGGL KCHRSFMGSR FIEVMQGSEQ QWIEFGGTAT
250 260 270 280 290 300
EGGDTPRMRS EEHSPSRRIN GRHFRKRSHS KSPRARSRSP LGFYVHLKNL SLNTNKRDLR
310 320 330 340 350 360
NLFRDTDLTN DQIKFVYKDE RRTRYAFVMF KNQKDYNTAL GLHKTVLQYR PVLIDPVSRK
370 380 390 400 410 420
EMVRIIECYE KKRPESLEKE RPGRVSQKYS QEGFSGSGQK LCIYIRNLPF DVTKGEVQKF
430 440 450 460 470 480
FADFSLVEDD IYLLCDDKGV GLGEALVRFK SEEQAMKAER LNRQRFLGIE VLLRLISEEQ
490 500 510 520 530 540
MQEFGVKSSW LSNERTQACS RSHDGDDCSC LFDLKDPSSC SFGQSESLRY HPKDLRKMGH
550 560 570 580 590 600
FKHPQGYFRQ SDRRSPEDFR HSPEDYRHPW EEHTSHSREE DWRLPLEDWK WSQEDDFRQC
610 620 630 640 650 660
HEKDRRQLRS PWEEDFRRPS QEHFRRSYQE HIRQPPEEHF RRSREEDFRH VADEDFRQAS
670 680 690 700 710 720
DEDFRTSQED LRYPTDEDFR RVSVEDLREV PEKDLRLPKN FRSPGEEFWT PPDFRGQHPF
730 740 750 760 770 780
GNFDHLQGGK FDFEKYKFGS FPDAKVTSDL NLNCVSDKII PVKISNLPFK ANASEILDFF
790 800 810 820 830
HGYKVIPDSV SLQYNEQGLP IGEAIVAMTN YNEALAAVKD LSGRPVGPRK VKLSLL