Q7ZT42

PR
Gene name
snd1 (sn4tdr)
Protein name
Staphylococcal nuclease domain-containing protein 1
Names
100 kDa coactivator, 4SNc-Tudor domain protein, p100 co-activator
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:324404
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

22-100 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7ZT42

Entry ID Method Resolution Chain Position Source
AF-Q7ZT42-F1 Predicted AlphaFoldDB

No variants for Q7ZT42

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7ZT42

No associated diseases with Q7ZT42

No regional properties for Q7ZT42

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q7ZT42

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
RISC complex A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.

2 GO annotations of molecular function

Name Definition
nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
gene silencing by RNA A process in which an RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8NHU6 TDRD7 Tudor domain-containing protein 7 Homo sapiens (Human) PR
Q8K1H1 Tdrd7 Tudor domain-containing protein 7 Mus musculus (Mouse) PR
10 20 30 40 50 60
MASAVPAQVQ SSQASAPQLQ RGIVKMVLSG CAIIVRGQPR GGPPPERQIN LSNIRAGALA
70 80 90 100 110 120
RRAIQGQPDT KDTPDEPWAF QAREFMRKKV IGKEVCFTVE NKTPQGREYG MVYLGKDTSG
130 140 150 160 170 180
ENIAESLVAE GLAMVRREGI RGNNPEQVRL CDLEDQAKSS KKGLWSEGGG SHTIRDLKYT
190 200 210 220 230 240
IENPRNFVDS LHQKPVNAII EHVRDGCMVR ALLLPDYYLV TVMLSGIKSP TFKREADGSE
250 260 270 280 290 300
TPEPFAAEAK FFTESRLLQR DVQIILESCP NQVILGTILH PNGNITELLL KEGFARCVDW
310 320 330 340 350 360
SMAVYTQGAE KLRAAERSAK ERKVRIWKDY VAPTANLDQK DRQFVAKVMQ VVNADAIVVK
370 380 390 400 410 420
LNSGEYKTIH LSSIRPPRLE GEEKNKDKDK RFRPLYDIPY MFEAREFLRK KLIGKKVNVT
430 440 450 460 470 480
VDYIRAATNA MEMGVPAFPE RTCATVTIGG INIAEALVSK GLATVIRYRQ DDDQRSSHYD
490 500 510 520 530 540
ELLAAEARAI KNGKGLHSKK EVPIHRVADI SGETQKAKQF FPFLQRAGRS EAVVEYVFSG
550 560 570 580 590 600
SRLKLYMPKE TCLITFLLAG IECPRGSRNM PGGMQVAEPY SEEAMLFTKE LVLQREVEVE
610 620 630 640 650 660
VESMDIAGNF IDWLHIDGVN LSVALVENAL SKVHFTAERS SYYKTLVSAE ESARQRKEKL
670 680 690 700 710 720
WANYEEKPNE EVAQVTEAKE RGRNTDPSTS LEITDGLHFY AQDVETGTKL ENLMESMRGE
730 740 750 760 770 780
IAAQPPVEGS FAPRRGEFCI AKFADGEWYR ARVEKVESPA KVHVFYIDYG NREVLSSTRL
790 800 810 820 830 840
AALPPAFSTR TLPPQATEYA FAYIQVPQDE DARADAVDSV VRDIHNTQCL LNVEYSGMVC
850 860 870 880 890
PQVTLQFADT KEDVGLGLVK EGMVMVDIRK EKYLQKMVTE YLNAQESAKS ARLNIWR