Q719I0

PR
Gene name
AHSA2P
Protein name
Putative activator of 90 kDa heat shock protein ATPase homolog 2
Names
Activator of HSP90 ATPase homolog 2 pseudogene
Species
Homo sapiens (Human)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

84-217 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q719I0

Entry ID Method Resolution Chain Position Source
AF-Q719I0-F1 Predicted AlphaFoldDB

1 variants for Q719I0

Variant ID(s) Position Change Description Diseaes Association Provenance
VAR_038256 248 M>T a breast cancer sample; somatic mutation [UniProt] No UniProt

No associated diseases with Q719I0

No regional properties for Q719I0

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q719I0

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
ATPase activator activity Binds to and increases the activity of an ATP hydrolysis activity.
chaperone binding Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
Hsp90 protein binding Binding to Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.

2 GO annotations of biological process

Name Definition
positive regulation of ATP-dependent activity Any process that activates or increases the rate of an ATP-dependent activity.
protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q12449 AHA1 Hsp90 co-chaperone AHA1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
10 20 30 40 50 60
MAKWGQGNPH WIVEEREDGT NVNNWRWTER DATSLSKGKF QELLVGIVVE NDAGRGEINE
70 80 90 100 110 120
LKQVEGEASC SSRKGKLIFF YEWNIKLGWK GIVKESGVKH KGLIEIPNLS EENEVDDTEV
130 140 150 160 170 180
SLSKKKGDGV ILKDLMKTAG TAKVREALGD YLKALKTEFT TGMILPTKAM ATQELTVKRK
190 200 210 220 230 240
LSGNTLQVQA SSPVALGVRI PTVALHMMEL FDTTVEQLYS IFTVKELTNK KIIMKWRCGN
250 260 270 280 290
WPEEHYAMVA LNFVPTLGQT ELQLKEFLSI CKEENMKFCW QKQHFEEIKG SLQLTPLNG