Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6ZM63

Entry ID Method Resolution Chain Position Source
AF-Q6ZM63-F1 Predicted AlphaFoldDB

No variants for Q6ZM63

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6ZM63

No associated diseases with Q6ZM63

1 regional properties for Q6ZM63

Type Name Position InterPro Accession
active_site Glycoside hydrolase family 9, His active site 390 - 416 IPR018221

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9UHW5 GPN3 GPN-loop GTPase 3 Homo sapiens (Human) PR
Q6R518 Gpn3 GPN-loop GTPase 3 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MPRYAQLVMG PAGSGKSTYC ATMLEHCQAL NRSVQVVNLD PAAEHFEYPV IADIRELIQV
70 80 90 100 110 120
DDVMEDDSLR FGPNGGLIFC MEYFSNNFDW LEESLGHVED DYILFDCPGQ IELYTHLPVM
130 140 150 160 170 180
KQLVEQLQQW EFRVCGVFLV DSQFMVETFK FISGVMAALS AMVMLEIPQV NIMTKMDLLS
190 200 210 220 230 240
PKAKKEIEKY LDPDMYSMME DNSVALRSKK FSKLTKAICG LIDDYSMVRF LPFDRTDEEG
250 260 270 280
INIVLQHIDF SIQYGEDLEV KEPKEVDEEP SNSNFDAFFQ DTADS