Q6R518

PR
Gene name
Gpn3
Protein name
GPN-loop GTPase 3
Names
ATP-binding domain 1 family member C
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:360810
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

235-284 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6R518

Entry ID Method Resolution Chain Position Source
AF-Q6R518-F1 Predicted AlphaFoldDB

No variants for Q6R518

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6R518

No associated diseases with Q6R518

4 regional properties for Q6R518

Type Name Position InterPro Accession
domain Protein kinase domain 56 - 340 IPR000719
active_site Serine/threonine-protein kinase, active site 177 - 189 IPR008271
binding_site Protein kinase, ATP binding site 62 - 86 IPR017441
domain Glycogen synthase kinase 3, catalytic domain 51 - 343 IPR039192

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9UHW5 GPN3 GPN-loop GTPase 3 Homo sapiens (Human) PR
Q6ZM63 gpn3 GPN-loop GTPase 3 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MPRYAQLVMG PAGSGKSTYC STMVQHCEAL NRSVQVVNLD PAAEHFNYPV MADIRELIEV
70 80 90 100 110 120
DDVMEDDSLR FGPNGGLVFC MEYFANNFDW LENCLGHVED DYILFDCPGQ IELYTHLPVM
130 140 150 160 170 180
KQLVQQLEQW EFRVCGVFLV DSQFMVESFK FISGILAALS AMISLEIPQV NIMTKMDLLS
190 200 210 220 230 240
KKAKKEIEKF LDPDMYSLLE DSTGDLRSQK FKKLTKPVCG LVDDYSMVRF LPYDQSDEES
250 260 270 280
MNIVLQHIDF AIQYGEDLEF KEPKEHEEES SSMFDEYFQE RQNE