Q6P6V6
Gene name |
Gpr108 |
Protein name |
Protein GPR108 |
Names |
|
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:316136 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6P6V6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6P6V6-F1 | Predicted | AlphaFoldDB |
No variants for Q6P6V6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6P6V6 | |||||
No associated diseases with Q6P6V6
No regional properties for Q6P6V6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6P6V6 | |||
Functions
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| cis-Golgi network membrane | The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| trans-Golgi network | The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of toll-like receptor signaling pathway | Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway. |
| regulation of immune response | Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q91WD0 | Gpr108 | Protein GPR108 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVSERRGLS | GESPAQCRWE | YLSLLVLMLS | GCSGRIHRLT | LTGEKRADIQ | LNSFGFYTNG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SLEVELSLLR | LSLQETEDKF | PKVGFSLSRV | RSGSVRSYSS | RNSHECPLER | NSSNFLVLFL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| INIKDLQVQV | RKYGEQKLFI | SPGLLPEAPS | QSGPPKPDPT | GTPKDNHVIH | PSPKKMSAVK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EDQAKLTVPQ | VSGDKALPAG | HRHSSDGQPQ | SQPPTRGPSG | KEKDLVLGLG | HLNDSYNFSF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HIVIGSRAEE | GQYSLNFHNC | YNTIPGQEQP | FDLTVMIREK | NPEGFLSAAE | IPLFKLYLIM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SACFLAAGIF | WVSVLCKNTY | SVFKIHWLMA | ALAFTKSVSL | LFHSINYYFI | NSQGHPIEGL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AVMHYITHLL | KGALLFITIA | LIGSGWAFVK | YMLSDKEKKI | FGIVIPLQVL | ANVAYIVIES |
| 430 | 440 | 450 | 460 | 470 | 480 |
| REEGASDYGL | WKEILFLVDL | ICCGAILFPV | VWSIRHLQDA | SGTDGKVAVN | LAKLKLFRHY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| YVMVICYIYF | TRIIAILLRV | AVPFQWQWLY | QLLVESSTLA | FFVLTGYKFQ | PAGDNPYLQL |
| 550 | 560 | 570 | |||
| PQQEDEEDVQ | MEQVMTDSGF | REGLSKVNKT | ASGRELL |