Q6P1U0
Gene name |
donson |
Protein name |
Protein downstream neighbor of son homolog |
Names |
|
Species |
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
KEGG Pathway |
xtr:395018 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6P1U0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6P1U0-F1 | Predicted | AlphaFoldDB |
No variants for Q6P1U0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6P1U0 | |||||
No associated diseases with Q6P1U0
No regional properties for Q6P1U0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6P1U0 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| replication fork | The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. |
| replisome | A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| DNA damage checkpoint signaling | A signal transduction process that contributes to a DNA damage checkpoint. |
| DNA replication | The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. |
| mitotic G2 DNA damage checkpoint signaling | A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage. |
| nuclear DNA replication | The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. |
| replication fork protection | Any process that prevents the collapse of stalled replication forks. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9NYP3 | DONSON | Protein downstream neighbor of Son | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAELLPGYSP | SFKKPSEILR | LSRRRSRSEA | SKAGVSPFSP | GDVTKRVPGL | RPFSPGPNKG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AGVKRRNPFA | NLENTVCSPV | KRRAESVPEC | ASPEPRALVA | ARPSCWELGS | PSPQPPQFNS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VEDVIWGDPL | ADPLVKTESP | EKPATACETP | KGSVTFPADW | SLKTRLLFTS | SQSFSWADHL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KAQEEAQGLV | MHCRATAVSL | PHSIQEPKLS | TELRCAFQQS | LVHWVHPSFP | WVQLFPRIGI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DRKMVGKNSP | WSHDESLQQV | IMSEWALSFT | SLYNLLKAKL | CPYFYVCTYQ | FTVLFRAAGL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AGSDVITAVM | SPTTRGLREA | MKNEGITFTQ | PLVEEDPSKK | QKNSEANSQG | DITPKKENGN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TETDEVSDES | DEDESFSWLE | EMGVEDKIKK | PDSISIKLRK | EKNEVKLDHK | PESVVLVKGT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NTFTLLNFLI | NCKSIVAAAG | PQAGLPPTLL | SPVAFRGATM | QTLKARSVNV | KTQVRSGYKD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QFSLEITGPI | MPHSLHSLTM | LLQSAQRGSF | SAGFYSHDPT | AVFNTPIHPQ | AAKEISADLQ |
| 550 | 560 | 570 | |||
| NCGLHPSTVE | QLSQVNQLGK | LSLRHLELSD | YRYTWKS |