Q6NYP0

PR
Gene name
tmem208 (zgc:77041)
Protein name
Transmembrane protein 208
Names
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:404632
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

120-175 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6NYP0

Entry ID Method Resolution Chain Position Source
AF-Q6NYP0-F1 Predicted AlphaFoldDB

No variants for Q6NYP0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6NYP0

No associated diseases with Q6NYP0

No regional properties for Q6NYP0

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6NYP0

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuole A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
vacuolar protein processing Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3SZZ5 TMEM208 Transmembrane protein 208 Bos taurus (Bovine) PR
Q9CR96 Tmem208 Transmembrane protein 208 Mus musculus (Mouse) PR
10 20 30 40 50 60
MAPKGKVGTK GKKQIHEENQ DTLKFYSRII LGANAIYIAV NLLLFYNSSS FWTWFSLMFA
70 80 90 100 110 120
VAVYVGSYRS MSAMAKPAFA EDGSLLDGGI DLNMEQGMAE HLKDVILLTA IVQVLSTLSS
130 140 150 160 170
YFWYLWLLAP ARALHLLWVN FLGPWFSADS QAAPEENEKN DKKQRRQERR QMRRF