Q3SZZ5
Gene name |
TMEM208 |
Protein name |
Transmembrane protein 208 |
Names |
|
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:507222 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3SZZ5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3SZZ5-F1 | Predicted | AlphaFoldDB |
22 variants for Q3SZZ5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs462660391 | 26 | Y>F | No | EVA | |
| rs453176817 | 103 | K>E | No | EVA | |
| rs473196462 | 106 | I>T | No | EVA | |
| rs438551512 | 107 | L>P | No | EVA | |
| rs458139827 | 113 | Q>P | No | EVA | |
| rs444529740 | 121 | Y>F | No | EVA | |
| rs461386238 | 126 | W>R | No | EVA | |
| rs435939629 | 135 | Y>F | No | EVA | |
| rs435939629 | 135 | Y>S | No | EVA | |
| rs453148638 | 137 | L>R | No | EVA | |
| rs473303917 | 143 | G>A | No | EVA | |
| rs473303917 | 143 | G>D | No | EVA | |
| rs452362090 | 146 | F>Y | No | EVA | |
| rs475591985 | 149 | D>Y | No | EVA | |
| rs444592898 | 150 | S>R | No | EVA | |
| rs461400447 | 151 | G>V | No | EVA | |
| rs440354970 | 162 | Q>R | No | EVA | |
| rs460824263 | 163 | R>G | No | EVA | |
| rs446287634 | 165 | Q>K | No | EVA | |
| rs469447766 | 169 | Q>P | No | EVA | |
| rs483022487 | 172 | R>G | No | EVA | |
| rs450499074 | 173 | L>V | No | EVA |
No associated diseases with Q3SZZ5
No regional properties for Q3SZZ5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q3SZZ5 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| vacuole | A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| autophagy | The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. |
| vacuolar protein processing | Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPKGKVGTR | GKKQIFEENK | ETLKFYLRII | LGANAIYCLV | TLVVFYSSAS | FWAWMALLFS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LAVYGASYHS | MSSMARAAFS | EDGALVDGGM | DLNMEQGMAE | HLKDVILLTA | IVQVLSCFSL |
| 130 | 140 | 150 | 160 | 170 | |
| YIWSFWLLAP | GRALYLLWVN | VLGPWFTADS | GAPAPEHNEK | RQRRQERRQM | KRL |