Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6K6K7

Entry ID Method Resolution Chain Position Source
AF-Q6K6K7-F1 Predicted AlphaFoldDB

No variants for Q6K6K7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6K6K7

No associated diseases with Q6K6K7

1 regional properties for Q6K6K7

Type Name Position InterPro Accession
domain Anoctamin, dimerisation domain 157 - 381 IPR032394

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
UFM1 activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond.

2 GO annotations of biological process

Name Definition
protein modification by small protein conjugation A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.
protein ufmylation Covalent attachment of the ubiquitin-like protein UFM1 to another protein.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8VE47 Uba5 Ubiquitin-like modifier-activating enzyme 5 Mus musculus (Mouse) PR
10 20 30 40 50 60
MDEEQLRALL RDLDALKQRP DPAAIDRMRE RVAGMVTPAA AARSKIKDMS SEVVDSNPYS
70 80 90 100 110 120
RLMALQRMGI VDNYERIRDY SIAIVGIGGV GSVAAEMLTR CGIGRLLLYD YDTVELANMN
130 140 150 160 170 180
RLFFRPDQVG MTKTDAAVQT LSGINPDVTL ESYSLNITTV KGFETFLGSL KARSSDGRNT
190 200 210 220 230 240
GVDLVLSCVD NYEARMVVNQ ACNELGQTWM ESGVSEDAVS GHIQLLVPGE TACFACAPPL
250 260 270 280 290 300
VVASGVDERT LKREGVCAAS LPTTMGVVAG LLVQNALKYL LKFGQVSPYL GYNSLKDYFP
310 320 330 340 350 360
TMEMKPNPQC SNPACVQRQK EYMQSKPARD AAAKAKMEAE ASAADECPVH LDNDWNISVV
370 380 390 400 410 420
DDSDTVTPSI LSTGADSLPE GLVRELPTAD SYQEPVAPVT SGAIDDDLEE LQRQLDALNS
S