Q6DII7

PR
Gene name
skap1
Protein name
Src kinase-associated phosphoprotein 1
Names
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:448448
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

208-309 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6DII7

Entry ID Method Resolution Chain Position Source
AF-Q6DII7-F1 Predicted AlphaFoldDB

No variants for Q6DII7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6DII7

No associated diseases with Q6DII7

2 regional properties for Q6DII7

Type Name Position InterPro Accession
domain SH3 domain 283 - 344 IPR001452
domain Pleckstrin homology domain 109 - 214 IPR001849

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Cell membrane
  • Upon T-cell stimulation, translocates to lipid rafts at the cell membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
adaptive immune response An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q86WV1 SKAP1 Src kinase-associated phosphoprotein 1 Homo sapiens (Human) PR
10 20 30 40 50 60
MQGYDIPRDV ISLLKDAETY LAECLQNEKL SGRAREQRDE ILHSFGQIRN RYGVEFALKG
70 80 90 100 110 120
GEAAFTHTGQ DDYDDIHNAS YAPSQASDEV SVASDYVEND SEVEEELDKI FKQGYLERRK
130 140 150 160 170 180
KDHGFFGSEW QKRWCVLTTR AFLYYSSEKG KQPKNGFLIK DSLAQMMPYI RKDSRRDSCF
190 200 210 220 230 240
EVVTPNQQVF QFTAASPSDA RDWVEQIQFL VKDTQSTIIP YEDDEETYDD IESTESSPVV
250 260 270 280 290 300
GLTNDSENSL QEDDVYESIP GDEETEESED ENYEMKPGEP VIFYGDYYQG LWNCFSDNSD
310 320 330 340
ELSFERGDLI HILSKEYHAY GWWVGELDGI VGIVPKDYLT LAFDL