Q6DEZ7

PR
Gene name
esrp1 (rbm35a)
Protein name
Epithelial splicing regulatory protein 1
Names
RNA-binding motif protein 35A, RNA-binding protein 35A
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:448608
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

378-465 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6DEZ7

Entry ID Method Resolution Chain Position Source
AF-Q6DEZ7-F1 Predicted AlphaFoldDB

No variants for Q6DEZ7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6DEZ7

No associated diseases with Q6DEZ7

No regional properties for Q6DEZ7

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6DEZ7

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

2 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding Binding to an RNA molecule or a portion thereof.

3 GO annotations of biological process

Name Definition
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
regulation of RNA splicing Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6NXG1 ESRP1 Epithelial splicing regulatory protein 1 Homo sapiens (Human) PR
B2RYD2 Esrp1 Epithelial splicing regulatory protein 1 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MTAVSPDYLV VLFTTTAGAN GSKLGSDEKE VIQLLWKVIN LANKKVGELH EVTVRPDHLE
70 80 90 100 110 120
LTEECKEITR IEADSLYVAP QLEQALQQFN QSVGNELNIG VGTSFCICTD GQLHIRQVLH
130 140 150 160 170 180
PEASKKNILL PECFYSFFDL RKEFLKCCPG SSDTNELDVH AMASYLGFEK KSTRYRYGAS
190 200 210 220 230 240
EVDDMGDIIV TLISEPYNYK FSDPERVNYK FESGTCSKLE IIDDNTIIRA RGLPWQSSDQ
250 260 270 280 290 300
DIARFFKGLN IAKGGAALCL NAQGRRNGEA LVRFVSEEHR DLALQRHKHH MGNRYIEVYK
310 320 330 340 350 360
ATGEDFLKIA GGTSNEVAQF LSKENQVIVR MRGLPFTATA EEVLAFFGQQ CPVTGGKEGI
370 380 390 400 410 420
LFVTYPDNRP TGDAFVLFAC EEYAQNALKK HKELLGKRYI ELFRSTAAEV QQVLNRYSSA
430 440 450 460 470 480
PLIPLPTPPI IPVLPQPFIP PVNVRDCIRL RGLPYAATIE DILEFLGEFS ADIRTHGVHM
490 500 510 520 530 540
VLNHQGRPSG DSFIQMKSAD RAYLAAQKCH KKTMKDRYVE VFQCSAEEMN FVLMGGTLNR
550 560 570 580 590 600
NGLSPPPCKL PCLSPPSYTF PAQAAVIPTE AAALYQPSLL LNPRSLQPSA AYYPAGAQLF
610 620 630 640 650 660
MNYTAYYPSP PGSPSSLGFF PASASVSSIP PHNTGAMVRM QGLAYNSGVK EILNFFQGYQ
670 680
YSPEDGLLPV NDQARALLTH PKEWVCI