Q6AYN9
Gene name |
Ccdc181 |
Protein name |
Coiled-coil domain-containing protein 181 |
Names |
|
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:360867 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6AYN9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6AYN9-F1 | Predicted | AlphaFoldDB |
No variants for Q6AYN9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6AYN9 | |||||
No associated diseases with Q6AYN9
1 regional properties for Q6AYN9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Coiled-coil domain-containing protein 34/181 | 342 - 438 | IPR025259 |
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| manchette | A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments. |
| microtubule | Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. |
| sperm flagellum | A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| microtubule binding | Binding to a microtubule, a filament composed of tubulin monomers. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q80ZU5 | Ccdc181 | Coiled-coil domain-containing protein 181 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDEDKGIDSK | ESGEYEDDFE | KDLEWLINDK | EKSNGSMIEV | ACKKEDDLDQ | ELKEKETETE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LGPQLSDPDK | PPKDEALPRR | NDFISVPSIQ | PLDPISDSDS | ENSFQDSKPE | NQKDLEDEED |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EEVRRYIMEK | IIEANKLLQT | QEPVNDKRER | KLKFKDKLVD | LEVPPLEDSD | TCKVLLENET |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NMSGKLSQLC | ISGDLGQESM | LMSVTNGGCE | ENDRKILVER | DGKFELMNLQ | DIESQGFLPP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ISSANGMEHE | SSQLPLRSAN | LSVGGIKKEE | PEAKIHIMTL | SQAGEPLAQV | PQPPANPKNR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PSSAANPDLN | KKTRRSSHRI | QSAGVSPVTS | TYCLSPRQKE | LQKQLERKRE | RLKREEEQRK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LEEENEKKKE | NEMVFKAWLQ | KKREQVVEMR | RVQRAKQIED | MSSRQVNRDP | QQAFRLWLKK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KHEEQMKERK | TEELRKQEEC | LFFLRGTEGR | ERAFRQWLRR | KQIEKIAEQQ | AVKERARQLR |
| 490 | 500 | ||||
| LEARRSKQLQ | SGLYSVPEAK | AFRFTDHYN |