Q6AVA8

PR
Gene name
PPDK1 (CPDK1, PPDKB)
Protein name
Pyruvate, phosphate dikinase 1, chloroplastic
Names
OsPPDKB, Pyruvate, orthophosphate dikinase 1
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4338750
EC number
2.7.9.1: Phosphotransferases with paired acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-117 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6AVA8

Entry ID Method Resolution Chain Position Source
AF-Q6AVA8-F1 Predicted AlphaFoldDB

No variants for Q6AVA8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6AVA8

No associated diseases with Q6AVA8

7 regional properties for Q6AVA8

Type Name Position InterPro Accession
domain PEP-utilising enzyme, C-terminal 591 - 945 IPR000121
domain Pyruvate phosphate dikinase, AMP/ATP-binding 93 - 130 IPR002192-1
domain Pyruvate phosphate dikinase, AMP/ATP-binding 138 - 364 IPR002192-2
domain Pyruvate phosphate dikinase, AMP/ATP-binding 377 - 430 IPR002192-3
domain PEP-utilising enzyme, mobile domain 496 - 577 IPR008279
active_site PEP-utilising enzyme, active site 524 - 535 IPR018274
conserved_site PEP-utilising enzyme, conserved site 837 - 855 IPR023151

Functions

Description
EC Number 2.7.9.1 Phosphotransferases with paired acceptors
Subcellular Localization
  • Plastid, chloroplast
  • Cytoplasm
  • Isoform 1 is targeted to the chloroplast while isoform 2 is found in the cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
metal ion binding Binding to a metal ion.
pyruvate, phosphate dikinase activity Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate.

3 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
photosynthesis The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.
pyruvate metabolic process The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q42368 PPDK2 Pyruvate, phosphate dikinase 2 Zea mays (Maize) PR
P11155 PPDK1 Pyruvate, phosphate dikinase 1, chloroplastic Zea mays (Maize) PR
O23404 PPDK Pyruvate, phosphate dikinase 1, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MPSVSRAVCV QRASGNNGRR CRDGAAAAGR RSVVAQRARH GKPEVAIRSG SGGSARGGHC
70 80 90 100 110 120
SPLRAVAAPI PTTKKRVFHF GKGKSEGNKA MKDLLGGKGA NLAEMASIGL SVPPGFTVST
130 140 150 160 170 180
EACQQYQAAG KTLPAGLWEE IVEGLQWVEE YMAARLGDPA RPLLLSVRSG AAVSMPGMMD
190 200 210 220 230 240
TVLNLGLNDE VAAGLAAKSG DRFAYDSYRR FLDMFGNVVM DIPHALFEEK LEAMKAVKGL
250 260 270 280 290 300
HNDTDLTATD LKELVAQYKD VYVEAKGEPF PSDPKKQLQL AVLAVFNSWD SPRAIKYRSI
310 320 330 340 350 360
NKITGLKGTA VNVQTMVFGN MGNTSGTGVL FTRNPSTGEK KLYGEFLVNA QGEDVVAGIR
370 380 390 400 410 420
TPEDLDAMRD HMPEPYEELV ENCKILESHY KEMMDIEFTV QENRLWMLQC RTGKRTGKGA
430 440 450 460 470 480
VKIAVDMVNE GLVERRTALK MVEPGHLDQL LHPQFENPSG YKDKVIATGL PASPGAAVGQ
490 500 510 520 530 540
IVFTAEDAEA WHAQGKDVIL VRTETSPEDV GGMHAAVGIL TARGGMTSHA AVVARGWGKC
550 560 570 580 590 600
CVSGCSSVRV NDASKIVVIE DKALHEGEWL SLNGSTGEVI IGKQPLCPPA LSGDLETFMS
610 620 630 640 650 660
WVDEVRKLKV MANADTPEDA TTARQNGAEG IGLCRTEHMF FASDERIKAV RQMIMASSLE
670 680 690 700 710 720
LRQKALDRLL PYQRSDFEGI FRAMDGLPVT IRLLDPPLHE FLPEGHVEDM VRELCSETGA
730 740 750 760 770 780
AQDDVLARVE KLSEVNPMLG FRGCRLGISY PELTEMQARA IFEAAITMTN QGIQVFPEIM
790 800 810 820 830 840
VPLVGTPQEL GHQVDVIRQI ANKVFTDMGK TIGYKVGTMI EIPRAALVAD EIAEQAEFFS
850 860 870 880 890 900
FGTNDLTQMT FGYSRDDVGK FLPIYLSQGI LQHDPFEVLD QRGVGELVKL ATERGRKARP
910 920 930 940
NLKVGICGEH GGEPLSVAFF AKAGLDYVSC SPFRVPIARL AAAQVLL