Q6A1G3

PR
Gene name
fut10
Protein name
Alpha-(1,3)-fucosyltransferase 10
Names
Fucosyltransferase X, Fuc-TX, FucT-X, Galactoside 3-L-fucosyltransferase 10, Fucosyltransferase 10
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:444886
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

14-91 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6A1G3

Entry ID Method Resolution Chain Position Source
AF-Q6A1G3-F1 Predicted AlphaFoldDB

No variants for Q6A1G3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6A1G3

No associated diseases with Q6A1G3

1 regional properties for Q6A1G3

Type Name Position InterPro Accession
domain Fucosyltransferase, N-terminal 74 - 172 IPR031481

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
Golgi cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
alpha-(1->3)-fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->3) linkage.

2 GO annotations of biological process

Name Definition
fucosylation The covalent attachment of a fucosyl group to an acceptor molecule.
protein glycosylation A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9VUL9 FucTA Glycoprotein 3-alpha-L-fucosyltransferase A Drosophila melanogaster (Fruit fly) PR
Q11131 Fut7 Alpha-(1,3)-fucosyltransferase 7 Mus musculus (Mouse) PR
10 20 30 40 50 60
MNRMWEKKFW ISCFFIILFF ILVTLQVMVE LGRFEKRETK SFTVIDIKEQ KKPLLKHIKE
70 80 90 100 110 120
KSNSRLRHLK DNYPIMLWWS PLTGENGRLG QCGTDTCFFT INRTYLQDPM TKAILFYGTD
130 140 150 160 170 180
FNMTSLPLPR EISHEWALFH EESPKNNYKL FHEPAITLFN HTATFSRHSH LPLTSQYLEG
190 200 210 220 230 240
LQALRSKEYL ISIQKKNFLR KRLAPLAYVQ SDCDPPSDRD SYVQELMKYI AVDSYGECLH
250 260 270 280 290 300
NRDLPQQVNN PSSMDDSQFH HILAQYKFIL AFENAVCEDY ITEKLWRPLK LGAVPVYFGA
310 320 330 340 350 360
PNVENWLPSN KSAIIVGRFS HPKELATYIK KLDKNDKLYM QFIEWKLHGN INNKHLLSTI
370 380 390 400 410 420
TERKWGVQDV TQDNYIDAFE CMICKRVWEN VRLKDRVSTT KLWNAESLHL NCPAPEAFSF
430 440 450 460 470
LPGHLLKSSM REMWKPSFEQ SKKEAKALRT LVDRNRNFTT VEFWNLVFKF Q