Q68FW2

PR
Gene name
Cdca3 (Tome1)
Protein name
Cell division cycle-associated protein 3
Names
Trigger of mitotic entry protein 1, TOME-1
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:297594
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

150-221 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q68FW2

Entry ID Method Resolution Chain Position Source
AF-Q68FW2-F1 Predicted AlphaFoldDB

No variants for Q68FW2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q68FW2

No associated diseases with Q68FW2

2 regional properties for Q68FW2

Type Name Position InterPro Accession
domain Ubiquitin-conjugating enzyme E2 8 - 174 IPR000608
active_site Ubiquitin-conjugating enzyme, active site 82 - 97 IPR023313

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytosol
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
adherens junction A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
protein ubiquitination The process in which one or more ubiquitin groups are added to a protein.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q99618 CDCA3 Cell division cycle-associated protein 3 Homo sapiens (Human) PR
10 20 30 40 50 60
MGSTQSVSGT PARPLPRNKH VSRVADPRSP SAGIQRTPIQ VESSPQPNPP AEQLNSLKQA
70 80 90 100 110 120
QDPDPRSPTL GIARTPMKIS GPDSQCPLVK ELSEVFETEV SETEVSESIS SPVLGLPQET
130 140 150 160 170 180
PLSSELDLPP DPDPQVSLED QLLPWSQTEL NSKQVFAKEE AKQSTETMVS GQTSDKPSRD
190 200 210 220 230 240
PETPQSSGSK RSRRKTNNKV LGRSPLTILQ DDNSPGTLTL RQGKRPSALS ENVKDLKEGV
250 260 270
ILGTGRFLKA GGGAWEQNED HDKENQHFAL MES