Q60595

PR
Gene name
Xlr3a
Protein name
X-linked lymphocyte-regulated protein 3A
Names
Species
Mus musculus (Mouse)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-104 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q60595

Entry ID Method Resolution Chain Position Source
AF-Q60595-F1 Predicted AlphaFoldDB

9 variants for Q60595

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389558976 6 R>K No EVA
rs3389556419 22 L>P No EVA
rs3410378503 29 N>I No EVA
rs3389572533 42 D>V No EVA
rs3389578082 109 Q>* No EVA
rs3389572588 109 Q>E No EVA
rs3389541935 141 T>R No EVA
rs3389541950 169 S>T No EVA
rs3389578113 198 A>V No EVA

No associated diseases with Q60595

1 regional properties for Q60595

Type Name Position InterPro Accession
domain XLR/SYCP3/FAM9 domain 75 - 202 IPR006888

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
synaptonemal complex A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
meiotic cell cycle Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
spermatid development The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6P205 Xlr3b X-linked lymphocyte-regulated protein 3B Mus musculus (Mouse) PR
Q61806 Xlr3c X-linked lymphocyte-regulated protein 3C Mus musculus (Mouse) PR
10 20 30 40 50 60
MSSRERKATD TAGRHSRMDP NLSSDDSQNP GAVAAANREV LDAGREDIIS SGTERQQARK
70 80 90 100 110 120
EKQDLVQEFE EPPNKVLQEN REKFSRIMTS SFSAMEVKIK DVLKTQCEQR QKLCQDYSLQ
130 140 150 160 170 180
FTNLSRKLTS DAYKLKKQAE TLSNMFMEQQ KFIHETLTLQ KNRMEEFKSL CEKYLEKLEV
190 200 210 220
LRDSRGNSIA EELRRLIATL EIKLLMLHNQ QNTAAPPQSL LDVLFS