Q5ZLL6
Gene name |
MSMO1 (SC4MOL, RCJMB04_5j19) |
Protein name |
Methylsterol monooxygenase 1 |
Names |
C-4 methylsterol oxidase |
Species |
Gallus gallus (Chicken) |
KEGG Pathway |
gga:422423 |
EC number |
1.14.18.9: With another compound as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5ZLL6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5ZLL6-F1 | Predicted | AlphaFoldDB |
No variants for Q5ZLL6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5ZLL6 | |||||
No associated diseases with Q5ZLL6
1 regional properties for Q5ZLL6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Fatty acid hydroxylase | 145 - 274 | IPR006694 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.18.9 | With another compound as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| C-4 methylsterol oxidase activity | Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + 6 Fe(II)- + 5 H+ + 3 O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + 6 Fe(III)- |
| iron ion binding | Binding to an iron (Fe) ion. |
| oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| sterol biosynthetic process | The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| F4JLZ6 | SMO1-3 | Methylsterol monooxygenase 1-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVNDSVNIL | NSAYLAVEYI | DSFLPDNPLQ | QPFKNAWNYM | LDNYTKFQIA | TWGSLLVHEA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SYFLLCVPGF | IFQFIPYMQK | YKIQPDKPET | WEKQWKCFKT | LIFNHFFIQL | PLICGTYYFT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EYFNIPYEWE | EMPRWYVLLA | QCFGCAVIED | AWHYFLHRLL | HHKRIYKYIH | KVHHEFVSPF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GMQAEYAHPL | ETLILGAGFF | IGIVVFCNHV | VLLWAWVICR | LMETIDVHSG | YDIPLNPLHL |
| 250 | 260 | 270 | 280 | 290 | |
| VPFYAGARFH | DFHHMNFIGN | YASTFTWWDR | IFGTDSQFIA | YKEKEKKQQL | RMKKTN |