Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5ZL79

Entry ID Method Resolution Chain Position Source
AF-Q5ZL79-F1 Predicted AlphaFoldDB

No variants for Q5ZL79

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5ZL79

No associated diseases with Q5ZL79

1 regional properties for Q5ZL79

Type Name Position InterPro Accession
domain Nucleolar protein 11 domain 200 - 243 IPR012584

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
maturation of SSU-rRNA Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.
positive regulation of transcription of nucleolar large rRNA by RNA polymerase I Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3MHH2 NOL11 Nucleolar protein 11 Bos taurus (Bovine) PR
Q9H8H0 NOL11 Nucleolar protein 11 Homo sapiens (Human) PR
10 20 30 40 50 60
MAALCEAFTL CGLGPAGGVG LGSGLLALEP GADPDHVLLT DRGRTTTLFK VSDQKPLGCW
70 80 90 100 110 120
SVKHGQIITC PVVCNFETHE YIAVHDNKVL RIWKDEDVNL DKVFKATLSA EVYRIHSLPH
130 140 150 160 170 180
AEPLVLFKGG GVRTLDVLLE APQQEIENVI SDEVIKWSEA FLESRQPVLI FVTEKDGDFF
190 200 210 220 230 240
VYVQKPKMRS LHKYKLEQQE LCNPLSFTAY IKKQIITLLC LYSSDSVYKV LIPLQQSSEE
250 260 270 280 290 300
EEQTSSKSLL LNLSISGSVL KGTSFVVLDK DHVAVLGSLA ASGEESKECL TIWNTKFQTL
310 320 330 340 350 360
QASKELPLGT SGQLWCYGEK FFFTHGKVLT VVIYKCETSS LAAAVGKLKD SQTSDLSSFV
370 380 390 400 410 420
NWNTLGDEEL LVSLQSQQSV ALKSESKMTL RSKKSAVANI QPDTSTVGQF LLSIKDASTA
430 440 450 460 470 480
AVEDQLRQLL SKAQMPDFQA TIGCIISALI NRCKTDPKFY PRNFLVQMIQ KGELSYSLCP
490 500 510 520 530 540
DLMAVALEKK DVHLLQICLQ RFPDIPEEIT YACLKVFLSI SDDYLERTDV NLESVISYID
550 560 570 580 590 600
IEPNNKEVKT EVVENGFNTE LEEDGCDVTG MKETHMMDSV EFCPVGPQKA ALLNAVLHSA
610 620 630 640 650 660
YSETFLLPHL KDLPAQQAVL FLRYLHYLYV KCSEKINTTL PGILSPTISQ IMDWMCLLLD
670 680 690 700 710 720
AHFTVMVMLP EAKGLLSSMH RFVRAQVRLY SELNKIEGSL QELQRIKCQK HSQAYSIEVL
ELI