Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5ZI69

Entry ID Method Resolution Chain Position Source
AF-Q5ZI69-F1 Predicted AlphaFoldDB

No variants for Q5ZI69

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5ZI69

No associated diseases with Q5ZI69

No regional properties for Q5ZI69

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5ZI69

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial large ribosomal subunit The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A4FUC0 MRPL37 39S ribosomal protein L37, mitochondrial Bos taurus (Bovine) PR
Q9BZE1 MRPL37 39S ribosomal protein L37, mitochondrial Homo sapiens (Human) PR
10 20 30 40 50 60
MALRPVVLRR APAHSRGILT RPGPPRPRGP LPRTPWTTRG PPPDQLARVV ERRPVREQVE
70 80 90 100 110 120
LDTVTYAGRQ YFVPGLARPR FPPWDRGWRE PWHSPGPRYE DMPLRKERGC FICHQRVRML
130 140 150 160 170 180
EGVRQAQWLT KTKLVQGLPA KVLSIAENPA YQLQEQEEAV HRAVAHARLW ETTEVSPRRE
190 200 210 220 230 240
KYCPVLFEDL IHLCRSMSVK YPSLARRMLA RNYRIAATWE RESTLLQIRG LNGILMNSMT
250 260 270 280 290 300
PIPPVASKEE ILATKDHVLE TFYPISPTID LQEVNVYQEL NDTGFKDGYP YSHPHTLYFL
310 320 330 340 350 360
ESANKRPNRF RPEQLRAKML MFAFGNALAK AKVLYGNDPQ VLEQPIVVQS VGTDGQLFQF
370 380 390 400 410 420
LVFQLNTTDL VSNDGIKNLV WIDSDQNLYE SAQCVPEVKK RVVTKPTGIY GLQPETFKKF
LALYLHGTV