Q5XJW2
Gene name |
Gadd45gip1 (Mrpl59) |
Protein name |
Growth arrest and DNA damage-inducible proteins-interacting protein 1 |
Names |
39S ribosomal protein L59, mitochondrial, MRP-L59 |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:288916 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5XJW2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5XJW2-F1 | Predicted | AlphaFoldDB |
1 variants for Q5XJW2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs8162594 | 188 | K>* | No | EVA |
No associated diseases with Q5XJW2
No regional properties for Q5XJW2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5XJW2 | |||
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
| ribosome | An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mitochondrial ribosome binding | Binding to a mitochondrial ribosome. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| positive regulation of cell population proliferation | Any process that activates or increases the rate or extent of cell proliferation. |
| positive regulation of oxidative phosphorylation | Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation. |
2 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAPATRSRY | LLRLTVTLGP | RSRSYHAPPP | PRRRPAPHWP | DRENLMTPRW | QLTPRYAAKQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FGRHGAISGV | PPASLWPSSE | QLCELEAEER | EWYPSLATMQ | ESLRVQQQAA | EARRQAREQH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IAECMAKMPQ | MIENWRKQKR | ERWEKIQADK | ERRARLQAEA | QEQLGYHVDP | RSARFQELLQ |
| 190 | 200 | 210 | 220 | ||
| DLDKQQRKRL | KEERQRQKKE | ARIAAMASAE | GQDSAEAQDS | AASGKPSS |