Q5XH95

PR
Gene name
slc25a25 (scamc2)
Protein name
Calcium-binding mitochondrial carrier protein SCaMC-2
Names
Small calcium-binding mitochondrial carrier protein 2, Solute carrier family 25 member 25
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:496462
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-82 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5XH95

Entry ID Method Resolution Chain Position Source
AF-Q5XH95-F1 Predicted AlphaFoldDB

No variants for Q5XH95

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5XH95

No associated diseases with Q5XH95

5 regional properties for Q5XH95

Type Name Position InterPro Accession
domain EF-hand domain 55 - 123 IPR002048-1
domain EF-hand domain 122 - 193 IPR002048-2
repeat Mitochondrial substrate/solute carrier 228 - 316 IPR018108-1
repeat Mitochondrial substrate/solute carrier 322 - 409 IPR018108-2
repeat Mitochondrial substrate/solute carrier 419 - 508 IPR018108-3

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

2 GO annotations of molecular function

Name Definition
ATP transmembrane transporter activity Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.
calcium ion binding Binding to a calcium ion (Ca2+).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8BVN7 Slc25a41 Calcium-independent mitochondrial carrier protein SCaMC-3L Mus musculus (Mouse) PR
Q19529 F17E5.2 Probable calcium-binding mitochondrial carrier F17E5.2 Caenorhabditis elegans PR
10 20 30 40 50 60
MARPRSLVSP LLSGVFCQCD TVGGAPHTHD TPASPSLAAA LAADPCGGLV CGGPEHETRL
70 80 90 100 110 120
QILFQELDVN KDGGICINDL AVGLKRLGVH RTELELRKIV KAGDKDQDGQ LDFEEFVHYL
130 140 150 160 170 180
RDHEKKLRLV FKSLDKKNDG RIDAQEIMQS LRDLGVNISE QQAEKILKSM DKNGTMTIDW
190 200 210 220 230 240
NEWRDYHLLH PAENIPEIIL YWKHSTIFDV GENLLVPDEF TVEEKQTGMW WRHLVAGGGA
250 260 270 280 290 300
GAVSRTCTAP LDRLKVLMQV HASRSNNMSM LGGFTQMIRE GGIRSLWRGN GINVIKIAPE
310 320 330 340 350 360
SAIKFMAYEQ MKRIIGSDQE TLGIHERLVA GSLAGVIAQS SIYPMEVLKT RMALRKTGQY
370 380 390 400 410 420
QGMLDCGKKI LLKEGVSAFY KGYVPNMLGI IPYAGIDLAV YETLKNAWLQ RYATSSADPG
430 440 450 460 470 480
VFVLLACGTI SSTCGQLASY PLALVRTRMQ AEASVEGAPQ MTMSKLFKHI VKTEGAFGLY
490 500 510
RGLAPNFMKV IPAVSISYVV YENLKLTLGV QSR