Q19529

PR
Gene name
F17E5.2
Protein name
Probable calcium-binding mitochondrial carrier F17E5.2
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_F17E5.2
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-96 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q19529

Entry ID Method Resolution Chain Position Source
AF-Q19529-F1 Predicted AlphaFoldDB

No variants for Q19529

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q19529

No associated diseases with Q19529

7 regional properties for Q19529

Type Name Position InterPro Accession
domain EF-hand domain 70 - 105 IPR002048-1
domain EF-hand domain 136 - 207 IPR002048-2
repeat Mitochondrial substrate/solute carrier 242 - 332 IPR018108-1
repeat Mitochondrial substrate/solute carrier 338 - 428 IPR018108-2
repeat Mitochondrial substrate/solute carrier 435 - 526 IPR018108-3
binding_site EF-Hand 1, calcium-binding site 83 - 95 IPR018247-1
binding_site EF-Hand 1, calcium-binding site 149 - 161 IPR018247-2

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

2 GO annotations of molecular function

Name Definition
ATP transmembrane transporter activity Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.
calcium ion binding Binding to a calcium ion (Ca2+).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8BVN7 Slc25a41 Calcium-independent mitochondrial carrier protein SCaMC-3L Mus musculus (Mouse) PR
Q5XH95 slc25a25 Calcium-binding mitochondrial carrier protein SCaMC-2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MSVTAESPSL RGGSILENKQ ELIDLKNIGE HARTVQPFKT SKHQPLIQGS VSKEAAIATH
70 80 90 100 110 120
SALHFDLTPE KEKKIRDMYD RLDADNDGSI DIRDLTQALS LQAHIPASVA PKLLERMKSE
130 140 150 160 170 180
HSDRVTYADF TNYVIAHEAR LAEVFDKIDL NSDGEVDMAE IKSYCKEMGV NLDDQKAMSI
190 200 210 220 230 240
VKKMDQSGSS SVNLNEFQDF MLLYPSTDMR DMVDFWRHNL IIDIGEDGQV PEDFTPQELL
250 260 270 280 290 300
SGVWWRHLVA GGVAGAMSRT CTAPFDRIKV YLQVNSTKTN KLGVVSCVHL LHAEGGIKSF
310 320 330 340 350 360
WRGNGINVIK IAPESAMKFM CYDQIKRWMQ EYKGGAELST IERLLAGSSA GAISQTAIYP
370 380 390 400 410 420
MEVMKTRLAL RRTGQLDKGM FHFAHKMYTK EGIKCFYKGY LPNLLGIIPY AGIDLTVYES
430 440 450 460 470 480
LKSMYTKYYT EHTEPGVLAL LACGTCSSTC GQLASYPLAL VRTRLQARAI SPKNSTQPDT
490 500 510 520 530
MVGQFKHILQ TEGFTGLYRG ITPNFMKVIP AVSISYVVYE KVRKQLGATM T