Q5U3Z3

PR
Gene name
Isoc2 (Isoc2b)
Protein name
Isochorismatase domain-containing protein 2
Names
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:361501
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

46-124 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5U3Z3

Entry ID Method Resolution Chain Position Source
AF-Q5U3Z3-F1 Predicted AlphaFoldDB

No variants for Q5U3Z3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5U3Z3

No associated diseases with Q5U3Z3

1 regional properties for Q5U3Z3

Type Name Position InterPro Accession
domain Isochorismatase-like 16 - 162 IPR000868

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Localizes to the nucleus in the presence of CDKN2A
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q32KX0 ISOC2 Isochorismatase domain-containing protein 2 Bos taurus (Bovine) PR
P85094 Isoc2a Isochorismatase domain-containing protein 2A Mus musculus (Mouse) PR
10 20 30 40 50 60
MAAARASLGR IFPESSILFL CDMQEKLRDR VLYFPQIVSM AARMLKVARI LDVPVLLTEH
70 80 90 100 110 120
YPQGLGPTVP ELGAQGVRTM SKTSFSMVPP LQQELDKLPQ LKSVLLCGIE TQVCILNTAL
130 140 150 160 170 180
DLLDRGLQVH VAVDACSSQS EMNRLVALAR MQHSGVFLST SEALTLQLIK DAAHPQFKEI
190 200
QKILKEPVPE IGLLGFFQGM NNPLLPNSRP