Q5SSN7

PR
Gene name
Sft2d1
Protein name
Vesicle transport protein SFT2A
Names
SFT2 domain-containing protein 1
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:106489
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5SSN7

Entry ID Method Resolution Chain Position Source
AF-Q5SSN7-F1 Predicted AlphaFoldDB

9 variants for Q5SSN7

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389150418 13 D>V No EVA
rs3389138851 15 E>D No EVA
rs3389122666 60 G>S No EVA
rs3389412052 96 T>I No EVA
rs3389412052 96 T>K No EVA
rs226827458 100 A>T No EVA
rs3389345578 105 L>F No EVA
rs3412927051 115 A>S No EVA
rs3389152676 121 K>R No EVA

No associated diseases with Q5SSN7

No regional properties for Q5SSN7

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5SSN7

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5SSN7 Sft2d1 Vesicle transport protein SFT2A Mus musculus (Mouse) PR
Q5U3Y5 Sft2d1 Vesicle transport protein SFT2A Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MEKLRRVLSG QDDEEQGLTA QVLDASSLSF NTRLKWFVIC FVAGIFFSFL GTGLLWLPNG
70 80 90 100 110 120
MKLFAVFYTL GNLAALASTC FLMGPVKQLK KMFETTRLLA TIIMLLCLVF TLCAALWWRK
130 140 150
KGLALLFCIL QFLSMTWYSL SYIPYARDAV LKCCSSLLG