Q5SQS7

PR
Gene name
SH2D4B
Protein name
SH2 domain-containing protein 4B
Names
Species
Homo sapiens (Human)
KEGG Pathway
hsa:387694
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

7-310 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5SQS7

Entry ID Method Resolution Chain Position Source
AF-Q5SQS7-F1 Predicted AlphaFoldDB

2 variants for Q5SQS7

Variant ID(s) Position Change Description Diseaes Association Provenance
rs7075840
VAR_056987
 237 H>R No UniProt
dbSNP
VAR_056988
rs11817391
 239 S>L No UniProt
dbSNP

No associated diseases with Q5SQS7

2 regional properties for Q5SQS7

Type Name Position InterPro Accession
domain SH2 domain 323 - 417 IPR000980
domain SH2D4B, SH2 domain 317 - 419 IPR035839

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A6X942 Sh2d4b SH2 domain-containing protein 4B Mus musculus (Mouse) PR
10 20 30 40 50 60
MLQQILHDMY IDPELLAELS DVQKHILFYK MREEQLRRWK ERETWEALAQ DEGLRPPKTK
70 80 90 100 110 120
RASDKHIQWL LGADGEVWVW IMGEGPGDKP YEEISEELIA ERARLQAQRE AEELWRQKEA
130 140 150 160 170 180
EITKKFRDAL ANEKARILAE KWKVEMEDRK AAKVLEERIH EEFKRKEEEE RKRGEEQIRL
190 200 210 220 230 240
QEEQRAKELY WTLKQAQLHC QASEKEEREW EEQLRRSKAA DEERSRRAQR ARDEYRHHSL
250 260 270 280 290 300
RAIQKGTVAG LSSMFRELGQ SHEQEARLYH HLPDPGLPQP LALPVRTWER PLRPVSRDVI
310 320 330 340 350 360
VRWFKEEQLP RRAGFERNTK FIAPWFHGII SREDAEALLE NMTEGAFLVR VSEKIWGYTL
370 380 390 400 410 420
SYRLQKGFKH FLVDASGDFY SFLGVDPNRH ATLTDLVDFH KEEIITVSGG ELLQEPCGQR
430
DSPPDYHLLF E