A6X942
Gene name |
Sh2d4b |
Protein name |
SH2 domain-containing protein 4B |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:328381 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6X942
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6X942-F1 | Predicted | AlphaFoldDB |
18 variants for A6X942
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs246815443 | 92 | E>K | No | EVA | |
| rs3389275497 | 97 | E>K | No | EVA | |
| rs3389245514 | 105 | L>P | No | EVA | |
| rs3389245495 | 117 | Q>R | No | EVA | |
| rs3389285510 | 155 | L>W | No | EVA | |
| rs3405081824 | 184 | Q>P | No | EVA | |
| rs3389292474 | 202 | A>D | No | EVA | |
| rs48584745 | 225 | S>R | No | EVA | |
| rs3389335904 | 251 | L>I | No | EVA | |
| rs3389275501 | 257 | E>K | No | EVA | |
| rs3405103960 | 261 | N>H | No | EVA | |
| rs3389321163 | 277 | P>S | No | EVA | |
| rs3389327863 | 358 | Y>* | No | EVA | |
| rs3389311819 | 359 | T>S | No | EVA | |
| rs3389285462 | 373 | V>L | No | EVA | |
| rs3389311883 | 419 | Q>E | No | EVA | |
| rs3389315346 | 423 | P>L | No | EVA | |
| rs230871334 | 432 | E>C | No | EVA |
No associated diseases with A6X942
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5SQS7 | SH2D4B | SH2 domain-containing protein 4B | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLQQILQDMY | IDPELLAELS | DVQKHILFYK | MREEQLRRWR | EREAWDALAQ | AEGLRPAKVK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RASNKHLQWL | LGADGEVWVW | VMGEGPGDKP | YEEISEELIA | ERARLQAQKE | AEELWRQKEA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EITKKFRDAL | ANEKARILAE | KWKVEMEDRK | AAKILEERIH | EEFKRKEEEE | RRRGEEQIRL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QEEQRAKELY | WTLKQAQLHS | QASENEEREW | EEQLRRSKAA | DEERSRRAQR | ARDEYRRHSL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RAIQKGTVAG | LSTMFQELGQ | NHEQEARLYH | QLPDTSPPSP | LTGPDRTWER | PLRPLSREVI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VRWFKEEQLP | RRAGFERNTK | SIAPWFHGII | SRESAEDLLE | NMTEGAFLVR | VSEKIWGYTL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SYRLQRGFKH | FLVDASGDFY | SFLGVDPNRH | ATLTDLIDFH | KEEIITVSGG | ELLQEPCGQR |
| 430 | |||||
| DSPPDYHLLF | E |