Q5PR98
Gene name |
ndrg2 (zgc:101847) |
Protein name |
Protein NDRG2 |
Names |
|
Species |
Danio rerio (Zebrafish) (Brachydanio rerio) |
KEGG Pathway |
dre:494050 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5PR98
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5PR98-F1 | Predicted | AlphaFoldDB |
No variants for Q5PR98
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5PR98 | |||||
No associated diseases with Q5PR98
No regional properties for Q5PR98
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5PR98 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| nervous system development | The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
| signal transduction | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
| Wnt signaling pathway | The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTEMQEIAI | TEEKPLLPGQ | SDAVKDAEIA | ARILLDQGQE | HTVETPHGVL | HVTVHGSGNA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RRPAILTIHD | VGMDSKSCFS | TLFRFEEMQE | IVKNFTVVHI | DAPGQEEGAA | VYPAGYQYAS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MDQVSEMLPA | VLQFFNFRTI | IGVGVGAGAY | ILSRFTLNNP | EAVEGLVLVN | VDPNARGWMD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WAAHKLSNLT | SSLSDQIISH | LFSQQELSAN | TELIQTHRER | ITKAPNLLNI | ELFWKSYLGR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RDLSLDRNNT | FKCPVMLVVG | DQAPYEEAAV | ECNSKLDPTT | TSFLKMADAG | GMPQLTQPSK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LTEAFKYFIQ | GMGYMASSCM | TRLSRSRTTS | LSSSYSMEGS | RSRSRTLSQG | SQGGQLPPSP |
| SNTMEVSC |