Q5M962

PR
Gene name
Tmem204 (Clp24)
Protein name
Transmembrane protein 204
Names
Claudin-like protein 24
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:287129
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

28-113 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5M962

Entry ID Method Resolution Chain Position Source
AF-Q5M962-F1 Predicted AlphaFoldDB

No variants for Q5M962

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5M962

No associated diseases with Q5M962

No regional properties for Q5M962

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5M962

Functions

Description
EC Number
Subcellular Localization
  • Cell junction, adherens junction
  • Cell membrane ; Multi-pass membrane protein
  • Co-localizes with the beta-catenin adherins
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
adherens junction A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
lymph vessel development The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.
regulation of vascular endothelial growth factor receptor signaling pathway Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q0IIE5 TMEM204 Transmembrane protein 204 Bos taurus (Bovine) PR
Q9BSN7 TMEM204 Transmembrane protein 204 Homo sapiens (Human) PR
Q7TQI0 Tmem204 Transmembrane protein 204 Mus musculus (Mouse) PR
10 20 30 40 50 60
MTVQKLVATA VLVALVSLIL NNAAAFTPNW VYQTLEDGRK RSVGLWKSCW LVDRGKGGTS
70 80 90 100 110 120
PGTRTGQVDT HDCEVLGWGS ESAGFQESRG TVKLQFDMMR ACNLVATAAL AVGQITFILG
130 140 150 160 170 180
LTGLPLMSPE SQCWEEAMAA AFQLASFVLV IGLVTFYRIG PYTNLSWSCY LNIGACLLAT
190 200 210 220
LAAAMLIWNI LHRREDCMAP RVIVISRSLT ARFRRGLDND YVESPC