Q0IIE5
PR
Gene name |
TMEM204 (CLP24) |
Protein name |
Transmembrane protein 204 |
Names |
Claudin-like protein 24 |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:615464 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0IIE5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0IIE5-F1 | Predicted | AlphaFoldDB |
148 variants for Q0IIE5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs466190606 | 2 | T>P | No | EVA | |
| rs445300581 | 12 | L>V | No | EVA | |
| rs470015777 | 13 | V>G | No | EVA | |
| rs478558290 | 14 | A>T | No | EVA | |
| rs437138457 | 17 | S>P | No | EVA | |
| rs455638447 | 20 | L>I | No | EVA | |
| rs474081974 | 20 | L>P | No | EVA | |
| rs434660024 | 26 | F>V | No | EVA | |
| rs453167764 | 27 | T>A | No | EVA | |
| rs471588807 | 28 | P>T | No | EVA | |
| rs438520140 | 29 | N>H | No | EVA | |
| rs463405081 | 29 | N>S | No | EVA | |
| rs475412303 | 30 | W>G | No | EVA | |
| rs442362231 | 33 | Q>P | No | EVA | |
| rs110680198 | 35 | L>M | No | EVA | |
| rs460926944 | 36 | E>D | No | EVA | |
| rs481018913 | 39 | R>Q | No | EVA | |
| rs459826853 | 41 | R>C | No | EVA | |
| rs450218663 | 54 | R>W | No | EVA | |
| rs470075090 | 55 | P>R | No | EVA | |
| rs437211606 | 56 | R>G | No | EVA | |
| rs133759961 | 58 | A>G | No | EVA | |
| rs467781440 | 61 | P>R | No | EVA | |
| rs465172890 | 68 | A>V | No | EVA | |
| rs457047485 | 75 | A>P | No | EVA | |
| rs475534255 | 78 | W>S | No | EVA | |
| rs442488739 | 79 | G>A | No | EVA | |
| rs454484652 | 81 | E>K | No | EVA | |
| rs473033746 | 88 | S>A | No | EVA | |
| rs441472382 | 89 | R>* | No | EVA | |
| rs438933663 | 93 | K>E | No | EVA | |
| rs437081478 | 96 | F>L | No | EVA | |
| rs452941282 | 107 | T>A | No | EVA | |
| rs471393911 | 108 | A>P | No | EVA | |
| rs431983849 | 111 | A>G | No | EVA | |
| rs135263631 | 112 | A>D | No | EVA | |
| rs135263631 | 112 | A>G | No | EVA | |
| rs456860140 | 112 | A>T | No | EVA | |
| rs443892910 | 113 | G>R | No | EVA | |
| rs443892910 | 113 | G>S | No | EVA | |
| rs474165491 | 114 | Q>P | No | EVA | |
| rs474165491 | 114 | Q>R | No | EVA | |
| rs478329809 | 115 | L>P | No | EVA | |
| rs459819704 | 115 | L>V | No | EVA | |
| rs482166079 | 116 | T>N | No | EVA | |
| rs463712232 | 116 | T>P | No | EVA | |
| rs449155807 | 117 | F>L | No | EVA | |
| rs434536152 | 118 | V>G | No | EVA | |
| rs467582166 | 118 | V>L | No | EVA | |
| rs467582166 | 118 | V>M | No | EVA | |
| rs432052879 | 119 | L>F | No | EVA | |
| rs465100079 | 119 | L>S | No | EVA | |
| rs446582298 | 119 | L>V | No | EVA | |
| rs475159410 | 121 | L>R | No | EVA | |
| rs456968620 | 121 | L>V | No | EVA | |
| rs437466472 | 122 | T>A | No | EVA | |
| rs455841766 | 122 | T>K | No | EVA | |
| rs474230695 | 123 | G>A | No | EVA | |
| rs459882456 | 124 | L>P | No | EVA | |
| rs459882456 | 124 | L>R | No | EVA | |
| rs438883028 | 125 | P>A | No | EVA | |
| rs463772442 | 125 | P>R | No | EVA | |
| rs461271692 | 126 | L>P | No | EVA | |
| rs461271692 | 126 | L>R | No | EVA | |
| rs442764285 | 126 | L>V | No | EVA | |
| rs479689998 | 127 | L>P | No | EVA | |
| rs479689998 | 127 | L>R | No | EVA | |
| rs465118928 | 128 | S>A | No | EVA | |
| rs477141899 | 128 | S>L | No | EVA | |
| rs465118928 | 128 | S>T | No | EVA | |
| rs468822756 | 129 | P>A | No | EVA | |
| rs454355785 | 130 | D>A | No | EVA | |
| rs467942168 | 130 | D>E | No | EVA | |
| rs435922656 | 130 | D>Y | No | EVA | |
| rs453534814 | 132 | Q>P | No | EVA | |
| rs471932279 | 133 | C>G | No | EVA | |
| rs471932279 | 133 | C>R | No | EVA | |
| rs438900138 | 134 | W>C | No | EVA | |
| rs475875610 | 135 | E>D | No | EVA | |
| rs457396975 | 135 | E>G | No | EVA | |
| rs442877082 | 136 | E>A | No | EVA | |
| rs461335057 | 136 | E>D | No | EVA | |
| rs442877082 | 136 | E>G | No | EVA | |
| rs479801512 | 137 | A>G | No | EVA | |
| rs458758274 | 138 | M>L | No | EVA | |
| rs450588210 | 139 | A>G | No | EVA | |
| rs477209979 | 139 | A>P | No | EVA | |
| rs468935300 | 140 | A>G | No | EVA | |
| rs480906832 | 141 | A>S | No | EVA | |
| rs466403411 | 144 | L>V | No | EVA | |
| rs435079771 | 145 | A>V | No | EVA | |
| rs380131493 | 146 | S>R | No | EVA | |
| rs476414998 | 148 | V>G | No | EVA | |
| rs455381121 | 149 | L>Q | No | EVA | |
| rs455381121 | 149 | L>R | No | EVA | |
| rs110746428 | 150 | V>L | No | EVA | |
| rs473603009 | 151 | I>M | No | EVA | |
| rs460722239 | 153 | L>V | No | EVA | |
| rs479095766 | 154 | V>G | No | EVA | |
| rs458297073 | 155 | T>P | No | EVA | |
| rs450111980 | 157 | Y>* | No | EVA | |
| rs483217597 | 157 | Y>C | No | EVA | |
| rs483217597 | 157 | Y>S | No | EVA | |
| rs468623662 | 158 | R>S | No | EVA | |
| rs447675943 | 159 | I>F | No | EVA | |
| rs451544240 | 160 | G>E | No | EVA | |
| rs433057973 | 160 | G>R | No | EVA | |
| rs449556044 | 163 | T>P | No | EVA | |
| rs1117970417 | 167 | W>R | No | EVA | |
| rs455316919 | 172 | N>T | No | EVA | |
| rs473692869 | 173 | I>S | No | EVA | |
| rs440800889 | 176 | C>Y | No | EVA | |
| rs452769169 | 180 | T>P | No | EVA | |
| rs471375121 | 185 | M>T | No | EVA | |
| rs439909655 | 186 | L>P | No | EVA | |
| rs439909655 | 186 | L>R | No | EVA | |
| rs458406460 | 188 | W>L | No | EVA | |
| rs483269858 | 190 | V>G | No | EVA | |
| rs462286195 | 192 | H>P | No | EVA | |
| rs480700308 | 192 | H>Q | No | EVA | |
| rs135737309 | 195 | E>G | No | EVA | |
| rs478206054 | 196 | D>G | No | EVA | |
| rs445091786 | 197 | C>R | No | EVA | |
| rs437020666 | 198 | T>I | No | EVA | |
| rs470092017 | 198 | T>P | No | EVA | |
| rs467329340 | 199 | A>D | No | EVA | |
| rs434469107 | 200 | P>H | No | EVA | |
| rs471385568 | 201 | R>H | No | EVA | |
| rs471385568 | 201 | R>P | No | EVA | |
| rs431908342 | 202 | V>G | No | EVA | |
| rs451958296 | 203 | I>S | No | EVA | |
| rs443881356 | 204 | V>A | No | EVA | |
| rs443881356 | 204 | V>G | No | EVA | |
| rs474371208 | 206 | S>R | No | EVA | |
| rs441348065 | 207 | R>L | No | EVA | |
| rs459790964 | 208 | S>P | No | EVA | |
| rs478296740 | 208 | S>Y | No | EVA | |
| rs445215533 | 209 | L>P | No | EVA | |
| rs449067314 | 210 | T>N | No | EVA | |
| rs482146497 | 210 | T>S | No | EVA | |
| rs467417184 | 211 | A>G | No | EVA | |
| rs434508133 | 212 | R>H | No | EVA | |
| rs446503563 | 213 | F>V | No | EVA | |
| rs465065114 | 214 | R>C | No | EVA | |
| rs432006017 | 214 | R>P | No | EVA | |
| rs456907584 | 215 | R>P | No | EVA | |
| rs476972739 | 217 | L>V | No | EVA | |
| rs437515150 | 220 | D>A | No | EVA |
No associated diseases with Q0IIE5
No regional properties for Q0IIE5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q0IIE5 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| adherens junction | A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| lymph vessel development | The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure. |
| regulation of vascular endothelial growth factor receptor signaling pathway | Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. |
| smooth muscle cell differentiation | The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTVRKVVATA | VLVALVSLVL | NNAAAFTPNW | VYQTLEDGRR | RSVGLWWACW | LVERPRGAPG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PGARPGPADV | RDCEALGWGS | EAAGFQESRG | TVKLQFDMMR | ACNLVATAAL | AAGQLTFVLG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LTGLPLLSPD | AQCWEEAMAA | AFQLASFVLV | IGLVTFYRIG | PYTSLSWSCY | LNIGACLLAT |
| 190 | 200 | 210 | 220 | ||
| LAAAMLIWNV | LHRREDCTAP | RVIVISRSLT | ARFRRGLDND | YVESPC |