Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5M8V6

Entry ID Method Resolution Chain Position Source
AF-Q5M8V6-F1 Predicted AlphaFoldDB

No variants for Q5M8V6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5M8V6

No associated diseases with Q5M8V6

1 regional properties for Q5M8V6

Type Name Position InterPro Accession
domain Histone H2A/H2B/H3 1 - 132 IPR007125

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
  • Found in the dense fibrillar compartment region of the nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.

1 GO annotations of biological process

Name Definition
ribosome biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8K013 Gtpbp10 GTP-binding protein 10 Mus musculus (Mouse) PR
10 20 30 40 50 60
MVWCCRPLLR KYGNFIDNLR IYVKGGAGGM GLPRLGGQGG KGGDVKLVAK KEVTLKKIKD
70 80 90 100 110 120
KFPHKRFIGG VGGNSSVRAL KGQPGEVCQV EVPSGIVITT EHGVKIGELD KEGDEIRVAR
130 140 150 160 170 180
GGQGGVFQTD FLPSKGQKRI IHLDLKLISD VGLVGFPNAG KSSLLSRISH AKPQVAEYAF
190 200 210 220 230 240
TTVKPELGRI MYPDYKQISV ADLPGLIEGA HYNRGMGHKF LKHIERTRQL LFVVDVAGFQ
250 260 270 280 290 300
LSASTLYRSA FETVLLLTLE LQLYKQELLD KPALLAVNKM DLPNANEKFE ELLKQLENPA
310 320 330 340 350 360
GNFHLLPDEL VPERPIEFKH IIPVSAATGQ GLENLIGCIR KTMDEQADME IRELAQERLQ
370 380
SLQKETSRTV KRNLKNSPQR THH