Q5E9P6
Gene name |
BSCL2 |
Protein name |
Seipin |
Names |
Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:513558 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5E9P6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5E9P6-F1 | Predicted | AlphaFoldDB |
No variants for Q5E9P6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5E9P6 | |||||
No associated diseases with Q5E9P6
Functions
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of endoplasmic reticulum membrane | The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| lipid droplet | An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| fat cell differentiation | The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. |
| lipid catabolic process | The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. |
| lipid droplet formation | A process that results in the assembly, arrangement of constituent parts of a lipid droplet. |
| lipid droplet organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle. |
| lipid storage | The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. |
| negative regulation of lipid catabolic process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVNDPPVPAL | LWAQEMGHVM | AGRARKLLLQ | FGVFFCTILL | LLWVSVFLYG | SFYYSYMPTV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SHLSPVHFHY | RTDCESSTSL | LCSFPVANVT | LAKGGRDRVL | MYGQPYRVTL | ELELPESPVN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QDLGMFLVTI | SCYTRGGRII | STSSRSVMLH | YRSSLLQMLD | TLVFSSLLLF | GFAEQKQLLE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VELYPEYREN | SYVPTTGAII | EIHSKRIQMY | GAYLRIHAHF | TGLRYLLYNF | PMTCAFVGVA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SNFTFLSVIV | LFSYMQWVWG | GIWPRQRLSL | QVNIRNRKRS | RKDIQRKVSA | HQPGPQGQEE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SPQLSPVTED | GESHADPSGT | EGQLSEEEKT | EQQPLSGEEE | LEPEASDGSG | SWEDAALLTE |
| 370 | 380 | 390 | |||
| ANLAASGSAP | APETVGSSEP | SAGSVRQRPI | CSSS |