Q58DQ5
Gene name |
MRPS9 |
Protein name |
28S ribosomal protein S9, mitochondrial |
Names |
MRP-S9, S9mt |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:519302 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
4 structures for Q58DQ5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 3JD5 | EM | 700 A | I | 1-396 | PDB |
| 6NEQ | EM | 332 A | I | 1-396 | PDB |
| 6NF8 | EM | 348 A | I | 1-396 | PDB |
| AF-Q58DQ5-F1 | Predicted | AlphaFoldDB |
70 variants for Q58DQ5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs442733154 | 2 | A>S | No | EVA | |
| rs453197995 | 3 | A>S | No | EVA | |
| rs441092973 | 13 | P>H | No | EVA | |
| rs520692128 | 21 | R>G | No | EVA | |
| rs478027994 | 22 | V>G | No | EVA | |
| rs443435661 | 24 | F>L | No | EVA | |
| rs463459609 | 26 | R>W | No | EVA | |
| rs722217547 | 34 | A>T | No | EVA | |
| rs445503444 | 44 | C>S | No | EVA | |
| rs465664637 | 45 | Q>P | No | EVA | |
| rs453694819 | 46 | I>M | No | EVA | |
| rs471238291 | 48 | R>W | No | EVA | |
| rs109424111 | 58 | T>K | No | EVA | |
| rs719393056 | 102 | E>K | No | EVA | |
| rs471236981 | 127 | H>Q | No | EVA | |
| rs135976854 | 185 | F>V | No | EVA | |
| rs134210017 | 194 | L>P | No | EVA | |
| rs380125082 | 219 | A>V | No | EVA | |
| rs517184122 | 223 | R>Q | No | EVA | |
| rs469482215 | 238 | E>V | No | EVA | |
| rs800478762 | 250 | V>I | No | EVA | |
| rs452004661 | 262 | Y>* | No | EVA | |
| rs714182090 | 264 | E>A | No | EVA | |
| rs438266501 | 268 | A>G | No | EVA | |
| rs444790624 | 271 | T>R | No | EVA | |
| rs461901094 | 311 | E>V | No | EVA | |
| rs478555401 | 316 | P>H | No | EVA | |
| rs447286837 | 320 | L>V | No | EVA | |
| rs478525045 | 324 | G>W | No | EVA | |
| rs450390278 | 326 | H>P | No | EVA | |
| rs470356053 | 327 | D>G | No | EVA | |
| rs449289467 | 328 | V>G | No | EVA | |
| rs435827425 | 328 | V>L | No | EVA | |
| rs466105217 | 330 | C>R | No | EVA | |
| rs434705242 | 330 | C>W | No | EVA | |
| rs451614698 | 331 | T>P | No | EVA | |
| rs456453408 | 332 | V>A | No | EVA | |
| rs456453408 | 332 | V>E | No | EVA | |
| rs456453408 | 332 | V>G | No | EVA | |
| rs433026623 | 332 | V>L | No | EVA | |
| rs476403591 | 333 | S>A | No | EVA | |
| rs441807821 | 333 | S>L | No | EVA | |
| rs476403591 | 333 | S>P | No | EVA | |
| rs476403591 | 333 | S>T | No | EVA | |
| rs472299067 | 337 | R>G | No | EVA | |
| rs440814392 | 338 | S>A | No | EVA | |
| rs477830822 | 339 | S>A | No | EVA | |
| rs464110531 | 341 | A>G | No | EVA | |
| rs449476946 | 342 | G>A | No | EVA | |
| rs466068748 | 343 | A>G | No | EVA | |
| rs445333133 | 344 | I>L | No | EVA | |
| rs465184547 | 344 | I>T | No | EVA | |
| rs437231844 | 345 | R>P | No | EVA | |
| rs456320162 | 346 | L>P | No | EVA | |
| rs470105989 | 347 | A>G | No | EVA | |
| rs435341768 | 348 | M>L | No | EVA | |
| rs455548030 | 349 | S>A | No | EVA | |
| rs440926995 | 352 | L>P | No | EVA | |
| rs451457861 | 353 | C>W | No | EVA | |
| rs471390525 | 361 | V>G | No | EVA | |
| rs439593004 | 370 | L>V | No | EVA | |
| rs458811493 | 371 | T>P | No | EVA | |
| rs378439729 | 372 | T>M | No | EVA | |
| rs482195951 | 374 | P>H | No | EVA | |
| rs381653809 | 378 | E>D | No | EVA | |
| rs481058652 | 383 | G>R | No | EVA | |
| rs446495562 | 386 | G>S | No | EVA | |
| rs447355449 | 387 | A>G | No | EVA | |
| rs460078169 | 387 | A>P | No | EVA | |
| rs476997056 | 392 | T>P | No | EVA |
No associated diseases with Q58DQ5
No regional properties for Q58DQ5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q58DQ5 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| mitochondrial small ribosomal subunit | The smaller of the two subunits of a mitochondrial ribosome. |
| small ribosomal subunit | The smaller of the two subunits of a ribosome. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P82933 | MRPS9 | 28S ribosomal protein S9, mitochondrial | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAPSVSCGA | AVPYRLFLAG | RVSFAREQGL | WKAAASGLQT | GTRCQILRLK | HSPAVTTTKN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VAALRRESYT | VDFIKKQIEE | FNIGKRHLAN | MMGEDPETFT | QEDVDRAITY | LFPSGLFEKR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ARPIMKHPEE | IFPKQRAVQW | GEDGRPFHFL | FYTGKQSYYS | LMHEAYGKVL | HAEERQDQLR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AKGLFSEKSK | SKDLIGSRWL | IKEELEEMLV | EKLSDQDYAQ | FIRLLERLSA | LPCDAAEEEF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VGRFRRTVTV | QSKKHLIEPL | QYDEQGMAFS | TGQGKRKTAN | AEAVVYGHGS | GKIEINGVDY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLYFPVTQDR | EQLMFPFHFL | DRLGKHDVTC | TVSGGGRSSQ | AGAIRLAMSR | ALCSFITEDE |
| 370 | 380 | 390 | |||
| VEWMRQAGLL | TTDPRVRERK | KPGQEGARRK | FTWKKR |