Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q58CU0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q58CU0-F1 | Predicted | AlphaFoldDB |
No variants for Q58CU0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q58CU0 | |||||
No associated diseases with Q58CU0
No regional properties for Q58CU0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q58CU0 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| histone acetyltransferase complex | A protein complex that possesses histone acetyltransferase activity. |
| kinetochore | A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. |
| MOZ/MORF histone acetyltransferase complex | A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. |
| NuA4 histone acetyltransferase complex | A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60). |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| chromatin organization | The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
| histone H2A acetylation | The modification of histone H2A by the addition of an acetyl group. |
| histone H3-K14 acetylation | The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone. |
| histone H4-K12 acetylation | The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone. |
| histone H4-K5 acetylation | The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone. |
| histone H4-K8 acetylation | The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAMHNKAAPP | QIPDTRRELA | ELVKRKQELA | ETLANLERQI | YAFEGSYLED | TQMYGNIIRG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WDRYLTNQKN | SNSKNDRRNR | KFKEAERLFS | KSSVTSAAAV | SALAGVQDQL | IEKREPGSGT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ESDTSPDFHN | QENEPNQEDP | EDLDGSVQGV | KPQKAASSTS | TGSHHSSHKK | RKNKNRHRID |
| 190 | |||||
| LKLNKKPRAD | Y |