Q562C7
Gene name |
Pum3 |
Protein name |
Pumilio homolog 3 |
Names |
|
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:499339 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q562C7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q562C7-F1 | Predicted | AlphaFoldDB |
No variants for Q562C7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q562C7 | |||||
No associated diseases with Q562C7
8 regional properties for Q562C7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Pumilio RNA-binding repeat | 164 - 199 | IPR001313-1 |
| repeat | Pumilio RNA-binding repeat | 200 - 235 | IPR001313-2 |
| repeat | Pumilio RNA-binding repeat | 236 - 272 | IPR001313-3 |
| repeat | Pumilio RNA-binding repeat | 349 - 384 | IPR001313-4 |
| repeat | Pumilio RNA-binding repeat | 385 - 421 | IPR001313-5 |
| repeat | Pumilio RNA-binding repeat | 423 - 459 | IPR001313-6 |
| domain | CPL domain | 433 - 571 | IPR012959 |
| domain | Pumilio homology domain | 136 - 489 | IPR033133 |
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromosome | A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. |
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of protein ADP-ribosylation | Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids. |
| regulation of translation | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEVKGKKKIT | GKSPQTSQGK | NKFHKNSESS | SAKAFPRKAA | KEGGPKVTSK | NFEKGATKPG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KKRVKQFKNK | PQGGKGPKDK | FQKANKFNKK | RKFQPDGKSD | ESAAKKPKWD | DFKKKKKELK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QNRQLSDKTN | YDVVVRAKHI | WESLRRKDCD | KEKRVKLMSD | LQKLIQGKIK | TIAFAHDSTR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VIQCLIQYGS | EEQRKWAFEE | LQGDLVELSK | AKYSRNIVKK | FLMYGSKPQI | AEIIRSFKGH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VRKMLRHSEA | SAIVEYAYND | KAILEQRNML | TEELYGNTFQ | LYKSADHPTL | EKVLEVQPGK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LELILDEMKQ | ILTPMAQKEA | VIKHSLVHKV | FLDFFTYAPP | KLRSELIEAI | REAVVYLAHT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HDGARVAMHC | LWHGTPKDRK | VIVKTMKTYV | EKIANGQYSH | LVLLAAFDCI | DDTKLVKQII |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ISEVISSLPS | IVNDKYGRKV | LLYLLSPRAP | AHLVPEIIQL | LQKGDGNAHS | KKDTAIRRRE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LLESISPALL | SYLQGHTREV | VLDKSVCVLV | SDILGSATGD | AQPAMDAIAG | LAAEELYPGG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KDGELHIAEH | PAGHLVLKWL | IEQDKKIKEN | GKEGCFAKTL | VECVGMKNLK | SWASINRGAI |
| 610 | 620 | 630 | 640 | ||
| VLSSLLQSCD | QDVVNKVKAG | LKTLIPTLEK | TKSTSKGIQT | LLEKLTA |