Q4QQU7

PR
Gene name
Grtp1
Protein name
Growth hormone-regulated TBC protein 1
Names
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:361180
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

243-289 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4QQU7

Entry ID Method Resolution Chain Position Source
AF-Q4QQU7-F1 Predicted AlphaFoldDB

No variants for Q4QQU7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4QQU7

No associated diseases with Q4QQU7

1 regional properties for Q4QQU7

Type Name Position InterPro Accession
domain Rab-GAP-TBC domain 38 - 234 IPR000195

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
GTPase activator activity Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

1 GO annotations of biological process

Name Definition
activation of GTPase activity Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5TC63 GRTP1 Growth hormone-regulated TBC protein 1 Homo sapiens (Human) PR
Q9D3N8 Grtp1 Growth hormone-regulated TBC protein 1 Mus musculus (Mouse) PR
10 20 30 40 50 60
MDPAERAQAA RARVPRIDPY GFERPEDFDY AAYEEFFSTY LVILTKRAIK WSKLLKGSGG
70 80 90 100 110 120
VRKSVTDLNR TFPDNVMFRK TADPCLQKTL YNVLLAYGLH NQDVGYCQGM NFIAGYLILI
130 140 150 160 170 180
TKNEEESFWL LDALVGRILP DYYSPAMLGL KTDQEVLAEL VRMKLPAVAA LMDGHGVLWT
190 200 210 220 230 240
LLVSRWFICL FVDILPVETV LRIWDCLFNE GSKIIFRVAL TLIKQHQEFI LEASSVPDIC
250 260 270 280
DKFKQITKGD FVTECHTFMQ KIFSEPGSLS MATITRLRES CRAALQAQS