Q3ZC61
Gene name |
MRFAP1 |
Protein name |
MORF4 family-associated protein 1 |
Names |
|
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:522338 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3ZC61
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3ZC61-F1 | Predicted | AlphaFoldDB |
33 variants for Q3ZC61
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs474452300 | 6 | I>L | No | EVA | |
| rs474452300 | 6 | I>V | No | EVA | |
| rs453168524 | 11 | E>A | No | EVA | |
| rs434708318 | 12 | P>T | No | EVA | |
| rs470780225 | 13 | E>G | No | EVA | |
| rs452228962 | 14 | E>G | No | EVA | |
| rs437248522 | 15 | V>G | No | EVA | |
| rs455075052 | 17 | V>A | No | EVA | |
| rs455075052 | 17 | V>G | No | EVA | |
| rs436367236 | 31 | V>D | No | EVA | |
| rs465537294 | 41 | A>E | No | EVA | |
| rs450206643 | 43 | S>C | No | EVA | |
| rs483077650 | 50 | Y>D | No | EVA | |
| rs463279955 | 70 | Q>H | No | EVA | |
| rs441702721 | 71 | V>G | No | EVA | |
| rs480802260 | 76 | E>K | No | EVA | |
| rs459301880 | 77 | S>R | No | EVA | |
| rs441058968 | 79 | L>P | No | EVA | |
| rs1114269843 | 87 | D>E | No | EVA | |
| rs470882852 | 90 | E>D | No | EVA | |
| rs443441218 | 96 | R>L | No | EVA | |
| rs455011628 | 99 | K>N | No | EVA | |
| rs476444443 | 99 | K>T | No | EVA | |
| rs436506552 | 102 | E>G | No | EVA | |
| rs466154459 | 104 | A>S | No | EVA | |
| rs432618445 | 105 | K>T | No | EVA | |
| rs465625585 | 113 | M>I | No | EVA | |
| rs483014511 | 115 | V>E | No | EVA | |
| rs467836424 | 118 | V>A | No | EVA | |
| rs448066820 | 125 | E>G | No | EVA | |
| rs480939142 | 126 | S>A | No | EVA | |
| rs459309132 | 126 | S>L | No | EVA | |
| rs477084901 | 127 | S>A | No | EVA |
No associated diseases with Q3ZC61
No regional properties for Q3ZC61
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q3ZC61 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| perinuclear region of cytoplasm | Cytoplasm situated near, or occurring around, the nucleus. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9Y605 | MRFAP1 | MORF4 family-associated protein 1 | Homo sapiens (Human) | PR |
| Q96HT8 | MRFAP1L1 | MORF4 family-associated protein 1-like 1 | Homo sapiens (Human) | PR |
| Q9CQL7 | Mrfap1 | MORF4 family-associated protein 1 | Mus musculus (Mouse) | PR |
| Q5M820 | Mrfap1 | MORF4 family-associated protein 1 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRPLDIVELA | EPEEVEVLEP | EEDFEQFLLP | VINEMREDIA | ALSREHGRAY | LRNRSKLWEM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DNMLIQIKTQ | VEASEESALN | HLQNPDDGAE | GRGTKRCEKA | EEKAKEIAKM | AEMLVELVRR |
| IEKSESS |