Q3ZBI3
Gene name |
RNASEH2B |
Protein name |
Ribonuclease H2 subunit B |
Names |
RNase H2 subunit B, Ribonuclease HI subunit B |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:509258 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3ZBI3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3ZBI3-F1 | Predicted | AlphaFoldDB |
58 variants for Q3ZBI3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs432387244 | 2 | A>G | No | EVA | |
| rs447557489 | 11 | A>P | No | EVA | |
| rs133526156 | 12 | S>R | No | EVA | |
| rs516680919 | 36 | V>A | No | EVA | |
| rs437771478 | 46 | G>R | No | EVA | |
| rs465180542 | 58 | P>A | No | EVA | |
| rs477335614 | 68 | E>A | No | EVA | |
| rs447717223 | 71 | H>N | No | EVA | |
| rs466066856 | 72 | S>Y | No | EVA | |
| rs436591516 | 77 | E>Q | No | EVA | |
| rs476467670 | 85 | L>P | No | EVA | |
| rs458685910 | 97 | L>V | No | EVA | |
| rs470658322 | 99 | H>N | No | EVA | |
| rs441215041 | 99 | H>P | No | EVA | |
| rs459566951 | 100 | Y>S | No | EVA | |
| rs481603022 | 104 | A>T | No | EVA | |
| rs448588305 | 106 | K>E | No | EVA | |
| rs478090422 | 144 | V>A | No | EVA | |
| rs469320640 | 144 | V>L | No | EVA | |
| rs480164112 | 150 | V>E | No | EVA | |
| rs459259099 | 152 | K>E | No | EVA | |
| rs448109459 | 153 | K>N | No | EVA | |
| rs436963224 | 154 | K>N | No | EVA | |
| rs469668174 | 154 | K>R | No | EVA | |
| rs445796670 | 155 | Y>F | No | EVA | |
| rs464497028 | 156 | Y>* | No | EVA | |
| rs435536903 | 158 | Y>* | No | EVA | |
| rs475021564 | 158 | Y>C | No | EVA | |
| rs453154006 | 158 | Y>N | No | EVA | |
| rs457429720 | 159 | S>R | No | EVA | |
| rs475894286 | 162 | K>N | No | EVA | |
| rs439874529 | 163 | T>K | No | EVA | |
| rs462416741 | 166 | W>R | No | EVA | |
| rs480831044 | 167 | L>I | No | EVA | |
| rs447947977 | 167 | L>Q | No | EVA | |
| rs385398949 | 168 | G>E | No | EVA | |
| rs434048194 | 172 | N>H | No | EVA | |
| rs449261054 | 179 | K>Q | No | EVA | |
| rs467821827 | 181 | N>S | No | EVA | |
| rs438116997 | 182 | K>M | No | EVA | |
| rs456672859 | 184 | N>H | No | EVA | |
| rs471900538 | 187 | A>P | No | EVA | |
| rs432816070 | 188 | R>L | No | EVA | |
| rs451266895 | 192 | T>S | No | EVA | |
| rs473108275 | 197 | G>V | No | EVA | |
| rs440112064 | 199 | Q>H | No | EVA | |
| rs461807497 | 200 | V>G | No | EVA | |
| rs441477050 | 249 | A>E | No | EVA | |
| rs451939111 | 287 | A>S | No | EVA | |
| rs473496367 | 290 | D>V | No | EVA | |
| rs434385068 | 292 | S>G | No | EVA | |
| rs452773248 | 293 | G>* | No | EVA | |
| rs474585877 | 299 | S>T | No | EVA | |
| rs1117067092 | 299 | S>Y | No | EVA | |
| rs441712109 | 302 | G>D | No | EVA | |
| rs463367043 | 303 | T>R | No | EVA | |
| rs475696280 | 305 | H>N | No | EVA | |
| rs439417232 | 305 | H>Q | No | EVA |
No associated diseases with Q3ZBI3
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| ribonuclease H2 complex | A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| ribonucleotide metabolic process | The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
| RNA catabolic process | The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARGADGGDG | ASVWQHVFLL | PEYLKDDSKK | MKSGLVFVKL | ANPCSGEGTI | YLFNMCLPQL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FEIKVFKEKN | HSWFINESVQ | SGGLLHFATP | VDPLFLLLHY | LIKADKESFQ | GKFQPLDQVV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MDDMFPDCIL | LLKLPELEKL | LQHVTEEKEV | DKKKYYKYSK | EKTLKWLGKK | VNQTMAALKT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NKVNVSARVQ | STAFFSGGQV | SSDKDEDYVR | YAHGLISDYI | PKQLSDDLSK | YLKLPEPPAS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VRNPPSKKAK | LSDEPVMAKE | DYTKFNSKDF | KTVKKNSKMT | AAQKALAKVD | KSGMKSIDSF |
| FGTKHVKKK |