Q3V1V3
Gene name |
Esf1 (Abtap) |
Protein name |
ESF1 homolog |
Names |
ABT1-associated protein |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:66580 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3V1V3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3V1V3-F1 | Predicted | AlphaFoldDB |
47 variants for Q3V1V3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs27217719 | 90 | S>N | No | EVA | |
| rs226255094 | 97 | K>E | No | EVA | |
| rs27217720 | 146 | Q>H | No | EVA | |
| rs258297335 | 151 | I>T | No | EVA | |
| rs51114206 | 168 | K>T | No | EVA | |
| rs27217721 | 173 | G>C | No | EVA | |
| rs247395671 | 185 | G>E | No | EVA | |
| rs259731833 | 269 | E>D | No | EVA | |
| rs29958536 | 270 | E>D | No | EVA | |
| rs579615252 | 289 | E>G | No | EVA | |
| rs3388589117 | 311 | D>VSDG* | No | EVA | |
| rs3388595134 | 320 | E>D | No | EVA | |
| rs3388592471 | 328 | R>* | No | EVA | |
| rs3388598015 | 339 | E>D | No | EVA | |
| rs3388591553 | 349 | M>V | No | EVA | |
| rs3388589429 | 379 | Y>* | No | EVA | |
| rs3388591600 | 387 | R>M | No | EVA | |
| rs3388582632 | 391 | E>K | No | EVA | |
| rs3388599422 | 514 | T>K | No | EVA | |
| rs3388594411 | 526 | L>W | No | EVA | |
| rs3388591607 | 538 | S>G | No | EVA | |
| rs3388595364 | 557 | G>V | No | EVA | |
| rs3388589448 | 559 | D>E | No | EVA | |
| rs3388598785 | 568 | D>N | No | EVA | |
| rs3388597221 | 596 | E>V | No | EVA | |
| rs3392276881 | 608 | S>R | No | EVA | |
| rs3388593891 | 611 | E>V | No | EVA | |
| rs3388582650 | 617 | L>* | No | EVA | |
| rs3388599443 | 627 | E>D | No | EVA | |
| rs3388595186 | 638 | R>G | No | EVA | |
| rs3388597405 | 677 | K>E | No | EVA | |
| rs245988506 | 682 | S>P | No | EVA | |
| rs3388582663 | 694 | D>Y | No | EVA | |
| rs3388597217 | 698 | Q>H | No | EVA | |
| rs3388595156 | 705 | L>F | No | EVA | |
| rs3388593908 | 712 | D>N | No | EVA | |
| rs3388592482 | 721 | K>R | No | EVA | |
| rs226031447 | 743 | V>L | No | EVA | |
| rs3388589493 | 754 | A>G | No | EVA | |
| rs3388598798 | 755 | R>W | No | EVA | |
| rs3388587620 | 757 | Q>R | No | EVA | |
| rs3388592499 | 783 | I>F | No | EVA | |
| rs3388598732 | 790 | H>E | No | EVA | |
| rs27217814 | 808 | D>E | No | EVA | |
| rs233897766 | 813 | T>A | No | EVA | |
| rs3388599384 | 827 | K>T | No | EVA | |
| rs3388582667 | 838 | A>S | No | EVA |
No associated diseases with Q3V1V3
5 regional properties for Q3V1V3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SNF2, N-terminal | 413 - 657 | IPR000330 |
| domain | Helicase, C-terminal | 673 - 827 | IPR001650 |
| domain | HARP domain | 199 - 269 | IPR010003-1 |
| domain | HARP domain | 286 - 357 | IPR010003-2 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 391 - 564 | IPR014001 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSKQEIMDD | QRFRRVSKDP | RFWEMPEKER | KVKIDKRFRA | MFHDKKFKLN | YAVDKRGRPI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SHSTTEDLKR | FYDLSDSDSD | LSDEESKILS | QKKAKQKKKQ | TKKEAKSIEK | PIEEKKKETK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KTDQKDSINK | HDLNNSERVQ | KMKNSQKPQK | IDSEISPKKD | NEEFLQNKKK | KRGTTDLSVE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ALPKGKLRTK | DSSTSEMVKS | STMSSSKAKR | EKQSVVPVIM | AKDNDGKMPD | EDALEEDSDS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ASELGSDEES | EDEIISDGKT | SADEDESEEE | DEEEEEDSEE | EEEEEEEDES | DSGPDLARGK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GNVETSSEDE | DDLADLFPEE | PGFEHAWREL | DKDAPRADEI | TRRLAVCNMD | WDRLKAKDLL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ALFNSFKPKG | GVVFSVKIYP | SEFGKERMKE | EQVQGPVELL | SIPEDAPEKD | WASREKLRDY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QFKRLKYYYA | VAECDSPETA | SKIYEDCDGL | EFESSCSFID | LRFIPDDITF | DDEPKDVALE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VDLTAYKPKY | FTSAAMGTST | VEITWDETDH | ERITTLNRKF | KKDELLDMDF | QAYLASSSED |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EEEVEEAPEG | EEGVNIGEDG | KTKKSQKDDE | EQIAKYRQLL | QVIQEKEKKG | KENDMEMEIK |
| 610 | 620 | 630 | 640 | 650 | 660 |
| WVPGLKESAE | EMVKNKLEGK | DKLTPWEQFL | EKKKEKKRLK | KKQKALAEED | SEDELPSDVD |
| 670 | 680 | 690 | 700 | 710 | 720 |
| FNDPYFAEEV | KKIGIKKKSM | KSAKDSASSE | EETDLEKQKA | EMALLVMDEE | EDSKKHFNYD |
| 730 | 740 | 750 | 760 | 770 | 780 |
| KIVEHQNLSK | KKKKQLMKKK | ELVEDDFEVN | VSDARFQAMY | TSHLFNLDPS | DPNFKKTKAM |
| 790 | 800 | 810 | 820 | 830 | 840 |
| EKILEEKARH | RERKEELLIQ | AVERAQQDTG | KPTQKQPMDP | ALSMLIKSVK | NKTEQFQARK |
| KQRVK |