Q3V079
Gene name |
Bbof1 |
Protein name |
Basal body-orientation factor 1 |
Names |
Coiled-coil domain-containing protein 176 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:72873 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3V079
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3V079-F1 | Predicted | AlphaFoldDB |
14 variants for Q3V079
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389222530 | 104 | K>T | No | EVA | |
| rs3403640111 | 121 | E>V | No | EVA | |
| rs3403294446 | 123 | L>W | No | EVA | |
| rs3389222514 | 244 | Y>N | No | EVA | |
| rs50006147 | 259 | I>M | No | EVA | |
| rs3403522888 | 276 | L>W | No | EVA | |
| rs217634264 | 331 | L>S | No | EVA | |
| rs3389210323 | 334 | I>V | No | EVA | |
| rs3403431154 | 403 | C>S | No | EVA | |
| rs51438239 | 437 | T>S | No | EVA | |
| rs3389245697 | 466 | F>I | No | EVA | |
| rs3389180340 | 508 | Q>* | No | EVA | |
| rs218348359 | 510 | P>S | No | EVA | |
| rs3389251289 | 521 | D>V | No | EVA |
No associated diseases with Q3V079
1 regional properties for Q3V079
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Domain of unknown function DUF4515 | 83 - 276 | IPR032777 |
Functions
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| ciliary basal body | A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| motile cilium assembly | The aggregation, arrangement and bonding together of a set of components to form a motile cilium. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPAKDKRKDK | RKDKRKGKNK | GKEPKKIIKS | DEPAIERAKA | NASLWEARLE | VTELSRIEYR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DTSRRLAKNN | EDLKKQQYNM | EKDIMSVLSY | LKKQDQEKDN | MIEKLKQQLA | KTKEKAQEEK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EKLEQKYALQ | VSELEGQFHQ | KAKEIGMIQT | ELKTIKQFQK | RKIQVEKELD | DLKENLRNSE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KNYQETLRRL | ESRFFEEKHR | LEQEAEKRII | MLAERAHHEA | VVQLNTAGRN | VFKENVYLHK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ALAYHLKEAE | ILQQNSKKIE | ENHSCLLQQK | EINDLLVKEK | IMQLTQQKSQ | IQTLQKKVVS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LENALTYMTT | EFEAEVLKLQ | QKAIIENQAG | LVEIDKLQQL | LQMKDREMNR | VKRLAKNILD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ERTEVEQFFL | DALYEVKQQI | LASRKHYKQI | AQAAFNLKMR | AACAGKTEYP | RIRTFDGKEQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| STNSVNQDLL | EAEKWPTTQK | NVDIRDLTWE | QKEKVLRLLF | AKMNGFAARK | YSQSSKPPVP |
| 490 | 500 | 510 | 520 | 530 | |
| DHIIYGSGEM | KETGDENNLL | DQTFITQQAP | VSDSNRMVSP | DVIPQGLQDS | DIA |