Q08C53

PR
Gene name
bbof1
Protein name
Basal body-orientation factor 1
Names
Coiled-coil domain-containing protein 176
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-62 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q08C53

Entry ID Method Resolution Chain Position Source
AF-Q08C53-F1 Predicted AlphaFoldDB

No variants for Q08C53

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q08C53

No associated diseases with Q08C53

No regional properties for Q08C53

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q08C53

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton, cilium basal body
  • Localizes to a polar structure adjacent to the basal body
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ciliary basal body A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
motile cilium assembly The aggregation, arrangement and bonding together of a set of components to form a motile cilium.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8ND07 BBOF1 Basal body-orientation factor 1 Homo sapiens (Human) PR
Q3V079 Bbof1 Basal body-orientation factor 1 Mus musculus (Mouse) PR
10 20 30 40 50 60
MPKKKGKGKG KGKGKGKGKK DGKHDSKADR ESEIEKLKSN ASLWEAKFTV TDISRLEYRE
70 80 90 100 110 120
AARALAKANE ELENQQYRAE KDTKDIIAFL KRTDFEKTAT IAALEEELKR ERAKSAQEKD
130 140 150 160 170 180
LLVAEYMQKI DALEEMFRQR SGDFQRMQGE LKTIKHYRKI KANLEEDLIS IREKMYVDGR
190 200 210 220 230 240
AHQESLARTE YKFYMARIRI EKEAEQKISQ LAEQAHYEAV DQLGAASQTV ITENIRLNEG
250 260 270 280 290 300
LDYHVKEAEQ LKRINVALTE KNSSLALFKE TNELMKKEAD SHVQSQHSEI SELTAKLSTL
310 320 330 340 350 360
EQALGIMSRE FEQERVEMER SAGVNNTELE ELEMLLAARE KELSKVKQLA QSIIEQRREL
370 380 390 400 410 420
ELFFHEALNH ARKEIKAQQQ HYRQEALKSY RWRMNEAHAG RLEFPRIRTF SNAPNSTNDV
430 440 450 460 470 480
QTELEDSDKW NNLRSSNVDI SDLTWEQKER LLNLLFAKLN GIKTRKAAHP PALSASSSEK
490 500 510
IQVSSDAGST VESPSMTFIT QMTMANMTSD PFVLPALKST