AiPD: Autoinhibited Protein Database

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

545-648 (Predicted disordered autoinhibitory region) PR

545-648 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q3UW53-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3388506263	84	R>G	No	EVA
rs3388503201	98	A>T	No	EVA
rs3388507501	100	E>D	No	EVA
rs3388503197	115	K>T	No	EVA
rs3388504290	125	V>M	No	EVA
rs3388503131	143	P>L	No	EVA
rs253875055	145	A>V	No	EVA
rs260907935	182	E>Q	No	EVA
rs3388505763	222	E>D	No	EVA
rs3388506525	322	L>Q	No	EVA
rs3388502017	323	T>I	No	EVA
rs225244089	380	H>R	No	EVA
rs263905949	380	H>Y	No	EVA
rs31622980	437	R>G	No	EVA
rs3388507133	445	L>F	No	EVA
rs3388507084	486	D>E	No	EVA
rs3388502014	503	T>I	No	EVA
rs3388505793	512	A>V	No	EVA
rs3388505816	537	E>*	No	EVA
rs222295242	546	E>Q	No	EVA
rs215160386	589	M>I	No	EVA
rs3388502036	596	P>L	No	EVA
rs264401759	612	L>P	No	EVA
rs3388504024	633	S>L	No	EVA
rs250860185	638	A>E	No	EVA
rs31953143	651	V>E	No	EVA
rs3390793167	668	L>P	No	EVA
rs223058681	669	S>R	No	EVA
rs238482054	671	H>P	No	EVA
rs3390784392	678	G>E	No	EVA
rs246177165	679	G>E	No	EVA
rs387842108	680	T>S	No	EVA
rs3390708307	680	T>S	No	EVA
rs220573639	692	E>D	No	EVA
rs3388507171	692	E>V	No	EVA
rs31347117	693	P>S	No	EVA
rs3388503176	696	V>M	No	EVA
rs3388506167	703	L>V	No	EVA
rs31646042	705	K>E	No	EVA
rs247555494	713	V>I	No	EVA
rs47778892	715	S>C	No	EVA
rs264087390	716	A>T	No	EVA
rs3390808538	726	G>R	No	EVA
rs3388505792	733	N>K	No	EVA
rs3388505754	745	A>P	No	EVA
rs32646612	746	S>G	No	EVA
rs244617003	761	V>I	No	EVA
rs31552250	766	A>T	No	EVA
rs581227759	766	A>V	No	EVA
rs239239629	769	L>M	No	EVA
rs212485928	823	I>L	No	EVA
rs3388503887	823	I>T	No	EVA
rs3390788595	840	V>L	No	EVA
rs3388502006	847	D>V	No	EVA
rs3388504062	878	S>N	No	EVA
rs3388506141	901	E>K	No	EVA
rs3388506120	903	T>A	No	EVA
rs225509332	906	T>N	No	EVA
rs3388508803	908	I>F	No	EVA
rs258459742	913	D>A	No	EVA
rs222970494	914	F>C	No	EVA

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q3UW53

		Description
EC Number
Subcellular Localization	Cytoplasm Membrane ; Lipid-anchor
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Name	Definition
No GO annotations for molecular function

Name	Definition
negative regulation of protein phosphorylation	Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
positive regulation of protein phosphorylation	Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
positive regulation of translation	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
response to endoplasmic reticulum stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q96TA1	NIBAN2	Protein Niban 2	Homo sapiens (Human)	PR