Q3UKC1
Gene name |
Tax1bp1 |
Protein name |
Tax1-binding protein 1 homolog |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:52440 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3UKC1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3UKC1-F1 | Predicted | AlphaFoldDB |
30 variants for Q3UKC1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs257653330 | 8 | Q>P | No | EVA | |
| rs3388828603 | 13 | N>D | No | EVA | |
| rs3388814308 | 21 | N>Y | No | EVA | |
| rs223115516 | 240 | S>L | No | EVA | |
| rs263539490 | 247 | E>V | No | EVA | |
| rs261721870 | 274 | Q>K | No | EVA | |
| rs3388826393 | 312 | E>K | No | EVA | |
| rs13463908 | 328 | C>S | No | EVA | |
| rs3388829343 | 353 | K>E | No | EVA | |
| rs3388832986 | 370 | L>F | No | EVA | |
| rs3388831405 | 383 | V>G | No | EVA | |
| rs3388835054 | 390 | D>Y | No | EVA | |
| rs3388819954 | 395 | R>C | No | EVA | |
| rs3388837751 | 438 | L>M | No | EVA | |
| rs3388816961 | 478 | T>I | No | EVA | |
| rs29896092 | 494 | T>A | No | EVA | |
| rs3388826363 | 494 | T>I | No | EVA | |
| rs219968063 | 503 | S>T | No | EVA | |
| rs29896944 | 505 | V>M | No | EVA | |
| rs3388830391 | 576 | E>K | No | EVA | |
| rs3388828531 | 590 | K>N | No | EVA | |
| rs3388831345 | 597 | E>* | No | EVA | |
| rs3388797015 | 598 | K>Q | No | EVA | |
| rs3388809478 | 600 | I>K | No | EVA | |
| rs237705562 | 618 | K>N | No | EVA | |
| rs29882946 | 628 | L>M | No | EVA | |
| rs3388814391 | 740 | G>E | No | EVA | |
| rs3388816995 | 791 | P>S | No | EVA | |
| rs3388830372 | 806 | F>V | No | EVA | |
| rs3388819946 | 809 | N>K | No | EVA |
No associated diseases with Q3UKC1
4 regional properties for Q3UKC1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Calcium binding and coiled-coil domain-like | 125 - 409 | IPR012852 |
| domain | SKICH domain | 17 - 120 | IPR041611 |
| domain | CALCOCO1/2, zinc finger UBZ1-type | 752 - 779 | IPR041641-1 |
| domain | CALCOCO1/2, zinc finger UBZ1-type | 779 - 806 | IPR041641-2 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| kinase binding | Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group. |
| metal ion binding | Binding to a metal ion. |
| ubiquitin binding | Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| apoptotic process | A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| negative regulation of apoptotic process | Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. |
| negative regulation of NF-kappaB transcription factor activity | Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSFQEVQLQ | TSNFAHVIFQ | NVAKSYLPNA | HLECHYTLTP | YIHPHSKDWV | GIFKVGWSTA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RDYYTFLWSP | MPEHYVEGST | VNCVLAFQGY | YLPNDDGEFY | QFCYVTHKGE | IRGASTPFQF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RAASPVEELL | TMEDEGNSDM | LVVTTKAGLL | ELKIEKTLKE | KEELLKLIAV | LEKETAQLRE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QVGRMERELS | QEKGRCEQLQ | AEQKGLLEVS | QSLRVENEEF | MKRYSDATAK | VQQLEEDIVS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VTHKAIEKET | DLDSLKDKLR | KAQHEREQLE | CQLQTEKDEK | ELYKVHLKNT | EIENTKLVSE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IQTLKNLDGN | KESMITHFKE | EISKLQSCLA | DKENLYRALL | LTTSNKEDTL | FLKEQLRKAE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EQVQATRQEL | IFLTKELSDA | VNVRDKTMAD | LHTARLENER | VKKQLADTLA | ELQLHAVKKD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QEKTDTLEHE | LRREVEDLKL | RLQMAADHYR | EKFKECQRLQ | KQINKLSDQA | ASTNSVFTKK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| MGSQQKVNDA | SINTDPAAST | SASAVDVKPA | ASCAETGFDM | STKDHVCEMT | KEIAEKIEKY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NKCKQLLQDE | KTKCNKYAEE | LAKMELKWKE | QVKIAENVKL | ELAEVEDNYK | VQLAEKEKEI |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NGLASYLENL | SREKELTKSL | EDQKGRKLEG | QSPQQVSRCL | NTCSEQNGLL | PPLSSAQPVL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| QYGNPYSAQE | TRDGADGAFY | PDEIQRPPVR | VPSWEDNVVC | SQPARNLSRP | DGLEDPEDSR |
| 730 | 740 | 750 | 760 | 770 | 780 |
| EDENVPIPPD | PANQHLRSHG | AGFCFDSSFD | VHKKCPLCEL | MFPPNYDQTK | FEEHVESHWK |
| 790 | 800 | 810 | |||
| VCPMCSEQFP | PDYDQQGFER | HVQTHFDQNV | LNFD |