AiPD: Autoinhibited Protein Database

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

584-670 (Predicted disordered autoinhibitory region) PR

584-670 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q2KJE0-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs460940564	90	Y>S	No	EVA
rs478954263	96	D>Y	No	EVA
rs518656329	147	A>T	No	EVA
rs436583736	199	L>V	No	EVA
rs467453026	201	A>T	No	EVA
rs478485757	205	A>G	No	EVA
rs444587274	207	T>N	No	EVA
rs458354771	207	T>S	No	EVA
rs444587274	207	T>S	No	EVA
rs475583078	209	V>G	No	EVA
rs461779428	210	S>L	No	EVA
rs441608888	211	Q>P	No	EVA
rs472783043	214	K>R	No	EVA
rs453105920	218	E>A	No	EVA
rs433081840	224	Y>*	No	EVA
rs798420102	249	E>K	No	EVA
rs436004016	364	Q>H	No	EVA
rs467404291	365	A>P	No	EVA
rs447255538	365	A>V	No	EVA
rs433751608	380	A>D	No	EVA
rs797603675	384	R>W	No	EVA
rs465254704	398	N>K	No	EVA
rs478956038	398	N>S	No	EVA
rs459195048	427	L>R	No	EVA
rs476919906	430	E>*	No	EVA
rs463211401	431	L>V	No	EVA
rs473902371	437	D>H	No	EVA
rs453780050	438	L>Q	No	EVA
rs451171371	439	K>N	No	EVA
rs471361397	439	K>Q	No	EVA
rs469244339	440	L>H	No	EVA
rs437937760	440	L>I	No	EVA
rs437937760	440	L>V	No	EVA
rs449080318	441	R>L	No	EVA
rs449080318	441	R>P	No	EVA
rs435305886	442	L>V	No	EVA
rs467724012	448	H>D	No	EVA
rs447661744	448	H>Q	No	EVA
rs478899421	449	Y>D	No	EVA
rs458979084	449	Y>S	No	EVA
rs445191858	450	K>N	No	EVA
rs483339608	451	E>K	No	EVA
rs483339608	451	E>Q	No	EVA
rs463174698	467	S>T	No	EVA
rs134744389	499	T>P	No	EVA
rs458440968	502	T>N	No	EVA
rs797391880	544	L>F	No	EVA
rs714594141	627	E>G	No	EVA
rs480859639	632	Q>L	No	EVA
rs876510816	658	Q>H	No	EVA
rs462212849	684	E>A	No	EVA
rs800992855	712	R>H	No	EVA
rs460142305	762	E>D	No	EVA
rs471528468	766	P>T	No	EVA
rs457854295	790	E>D	No	EVA

Type	Name	Position	InterPro Accession
domain	Calcium binding and coiled-coil domain-like	125 - 424	IPR012852
domain	SKICH domain	17 - 120	IPR041611
domain	CALCOCO1/2, zinc finger UBZ1-type	755 - 782	IPR041641-1
domain	CALCOCO1/2, zinc finger UBZ1-type	782 - 809	IPR041641-2

		Description
EC Number
Subcellular Localization	Cytoplasm Mitochondrion Preautophagosomal structure Cytoplasmic vesicle, autophagosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
No GO annotations for cellular component

Name	Definition
kinase binding	Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group.
metal ion binding	Binding to a metal ion.

Name	Definition
apoptotic process	A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
negative regulation of apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
negative regulation of NF-kappaB transcription factor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q86VP1	TAX1BP1	Tax1-binding protein 1	Homo sapiens (Human)	PR
Q3UKC1	Tax1bp1	Tax1-binding protein 1 homolog	Mus musculus (Mouse)	PR