Q3UHB1

PR
Gene name
Nt5dc3 (Gnn)
Protein name
5'-nucleotidase domain-containing protein 3
Names
GRP94-neighboring nucleotidase
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:103466
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-66 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3UHB1

Entry ID Method Resolution Chain Position Source
AF-Q3UHB1-F1 Predicted AlphaFoldDB

21 variants for Q3UHB1

Variant ID(s) Position Change Description Diseaes Association Provenance
rs231797092 33 S>A No EVA
rs216734988 53 S>N No EVA
rs3389096985 70 V>I No EVA
rs3389122227 86 N>T No EVA
rs3389125277 113 H>R No EVA
rs3389119279 150 Y>H No EVA
rs3389107803 163 F>L No EVA
rs3389119243 208 N>D No EVA
rs3389125341 253 R>K No EVA
rs3389122556 255 V>D No EVA
rs864285421 264 A>G No EVA
rs3389125311 304 V>I No EVA
rs3389112465 326 Q>* No EVA
rs3389097802 335 D>H No EVA
rs3389094148 415 L>F No EVA
rs3389130256 420 T>S No EVA
rs3389122549 441 Q>H No EVA
rs3389087181 494 F>S No EVA
rs3389119491 503 S>R No EVA
rs3389130292 522 Q>* No EVA
rs3389112439 543 A>T No EVA

No associated diseases with Q3UHB1

No regional properties for Q3UHB1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q3UHB1

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
receptor complex Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

2 GO annotations of molecular function

Name Definition
5'-nucleotidase activity Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
metal ion binding Binding to a metal ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3V1L4 Nt5c2 Cytosolic purine 5'-nucleotidase Mus musculus (Mouse) PR
10 20 30 40 50 60
MATVAAAARG AGARAAAGLR SCGGAVARER PRSGCARRLC SAPAAPAAVD MKSYLWARYH
70 80 90 100 110 120
EAKRSTDELV PSIMNNLLNP DAIFSNNEMS LSDIEIYGFD YDYTLVFYSK HLHTLIFNAA
130 140 150 160 170 180
RDLLINEHRY PVEIRKYEYD PSFAIRGLHY DVQRAVLMKI DAFHYIQMGT VYRGLSVVPD
190 200 210 220 230 240
EEVIDMYEGS HVPLEQMSDF YGKSSHGNTM KQFMDIFSLP EMTLLSCVNE HFLKNNIDYE
250 260 270 280 290 300
PVHLYKDVKD SIRDVHIKGI MYRAIEADIE KYICYADQTR AVLAKLAAHG KKMFLITNSP
310 320 330 340 350 360
SSFVDKGMRY IVGKDWRDLF DVVIVQAEKP NFFNDKRRPF RKVNEKGVLL WDKIHKLQKG
370 380 390 400 410 420
QIYKQGNLYE FLKLTGWRGS KVLYFGDHIY SDLADLTLKH GWRTGAIIPE LRSELRIMNT
430 440 450 460 470 480
EQYIQTMTWL QTLTGLLEQM QVHRDAESQL VLQEWKKERK EMREMTKSFF NAQFGSLFRT
490 500 510 520 530 540
DQNPTYFLRR LSRFADIYMA SLSCLLNYDV HHTFYPRRTP LQHELPAWSD SPSAFKAPLL
QEAQAK